微生物群落处理2萘磺酸钠后毒性效应的缓解

Q4 Pharmacology, Toxicology and Pharmaceutics

Toxicology International Pub Date : 2022-07-15 DOI:10.18311/ti/2022/v29i2/28165

Sukanya Mehra, P. Dhammi, P. Chadha, Harvinder Singh Saini

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引用次数: 0

摘要

本研究旨在对具有微生物联合体的染料中间体2萘磺酸(2NS)进行处理，并评估其处理前后对马尾鱼血细胞脱氧核糖核酸(DNA)完整性的潜在毒理学影响。彗星试验和微核试验显示，未经处理的2NS给药鱼的DNA损伤显著升高。然而，用混合菌群降解2NS后，2NS的毒理学效应显著降低。因此，本研究不仅说明了工业废水中有毒污染物的不良影响，而且提出了一种高效、环保的方法来去除环境中的有害外源物质，这可能有助于减少水生动植物对这类致命毒物的暴露。

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Mitigation of Toxic Effects of 2 Naphthalene Sulfonate after its Treatment with Microbial Consortia

Present study aimed to treat 2 Napthalene Sulfonate (2NS), a dye intermediate with microbial consortia and assess its potential toxicological impact before and after treatment on the integrity of Deoxyribo-Nucleic Acid (DNA) in blood cells of Channa punctatus. Symbolic elevation in DNA damage with untreated 2NS administered fishes was observed as revealed by comet assay and micronucleus test. However, 2NS after being degraded using mixed bacterial population showed significant reduction in toxicological effects of 2NS. Thus, this study not only illustrated the adverse impact of such toxic contaminant of industrial waste but also suggested a highly efficient and eco-friendly way to remove the harmful xenobiotics from the environment which may help to reduce the exposure of aquatic fauna and flora to such lethal toxicants.

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来源期刊

Toxicology International Environmental Science-Health, Toxicology and Mutagenesis

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： Toxicology International is a peer-reviewed International Research Journal published bi-annually by the Society of Toxicology, India. The Journal is concerned with various disciplines of Toxicology including man, animals, plants and environment and publishes research, review and general articles besides opinions, comments, news-highlights and letters to editor.