上颌骨感染的Presepsin评估：败血症的一种新的早期生物标志物？

Q4 Medicine

Italian journal of anatomy and embryology Pub Date : 2022-12-27 DOI:10.36253/ijae-13797

Luigi Falconio, O. Trubiani, D. Gazzolo, F. Valente, T. Traini

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引用次数: 0

摘要

牙源性感染可导致颌面部软组织和硬组织的严重炎症问题，即使在非常偏远的情况下，也会导致脑组织受累。因此，近年来，通过对口腔感染患者进行仔细的系统史研究，开发了一种治疗牙源性感染的整体诊断方法。在医院急诊室使用血清生物标志物，如聚合酶链式反应、降钙素原（PCT）和普雷塞肽（PSEP），有助于系统性败血症的早期检测。然而，即使联合使用，它们的诊断准确性也表明了研究新的、更特异的和敏感的生物标志物的重要性。共分析了9篇文章，以调查PSEP作为生物标志物在颌面部感染中的使用，仅包括2017年1月1日至2021年12月31日的英语文章和出版物的电子搜索。本研究旨在确定蛋白酶在牙源性感染引起的败血症中的诊断价值，并评估其在颌面外科手术干预预后评估阶段的应用。

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Presepsin assessment in maxillo-facial infections: a new early biomarker of sepsis?

Odontogenic infections can cause serious inflammatory problems of the soft and hard tissues in the maxillofacial area up to, albeit in quite remote circumstances, involvement of the brain tissues. In recent years, therefore, a holistic diagnostic-therapeutic approach has been developed in the management of odontogenic infections by carrying out a careful systemic history of the patient who has an infectious condition in the oral cavity. The early detection of systemic sepsis conditions was facilitated using serum biomarkers such as PCR, Procalcitonin (PCT) and Presepsin (PSEP) in hospital emergency rooms. However, even if used in combination, their diagnostic accuracy is such as to suggest the importance of researching new, more specific, and sensitive biomarkers. A total of 9 articles was analyzed to investigate the use of the PSEP as biomarker in the maxillo-facial region infections and including only English-language articles and the electronic search of publications from 1 January 2017 to 31 December 2021. This study aimed to determine the diagnostic value of presepsin in condition of sepsis derived from an odontogenic infection and to evaluate its use in the prognostic evaluation phase of surgical interventions performed in the maxillofacial area.

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来源期刊

Italian journal of anatomy and embryology Medicine-Embryology

CiteScore

0.20

自引率

0.00%

发文量

期刊介绍： The Italian Journal of Anatomy and Embryology, founded in 1901 by Giulio Chiarugi, Anatomist at Florence University, is a peer-reviewed journal sponsored by the Italian Society of Anatomy and Embryology. The journal publishes original papers, invited review articles, historical article, commentaries, obituitary, and book reviews. Its main focus is to understand anatomy through an analysis of structure, function, development and evolution. Priority will be given to studies of that clearly articulate their relevance to the anatomical community. Focal areas include: experimental studies, contributions based on molecular and cell biology and on the application of modern imaging techniques; comparative functional morphology; developmental biology; functional human anatomy; methodological innovations in anatomical research; significant advances in anatomical education. Studies that are essentially descriptive anatomy are appropriate only if they communicate clearly a broader functional or evolutionary significance. All papers should be submitted in English and must be original works that are unpublished and not under consideration by another journal. An international Editorial Board and reviewers from the anatomical disciplines guarantee a rapid review of your paper within two to three weeks after submission.