泌尿生殖系统肿瘤生物标志物尿外泌体的研究进展

Q4 Medicine

中华泌尿外科杂志 Pub Date : 2020-01-15 DOI:10.3760/CMA.J.ISSN.1000-6702.2020.01.018

Yalong Xu, Xi Chen, Jin Ji

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引用次数: 0

摘要

外泌体是包括肿瘤细胞在内的多种细胞分泌的膜性囊泡，具有稳定的特性，能反映来源细胞的生理/病理状态，是肿瘤早期诊断和预后的良好生物标志物来源。尿外泌体直接来源于泌尿系统，在泌尿系统肿瘤的诊断和预后中发挥更直接的作用。本文综述了泌尿生殖系统肿瘤早期诊断中泌尿外泌体作为分子标志物的研究进展。关键词:尿液;外来体;泌尿系肿瘤;生物标志物;诊断;预后

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Advances in the study of urinary exosomes as biomarkers of genitourinary tumors

Exosomes are membranous vesicles secreted by a variety of cells, including tumor cells, with stable characters, which can reflect the physiological/pathological state of the source cells, indicating good sources of biomarkers for early diagnosis and prognosis of tumors. Urine exosomes are directly derived from the urinary system and play a more direct role in the diagnosis and prognosis of urinary system tumors. This paper reviews the recent advances in urinary exosomes as molecular markers for the early diagnosis of genitourinary tumors. Key words: Urine; Exosome; Genitourinary tumors; Biomarkers; Diagnosis; Prognosis

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来源期刊

中华泌尿外科杂志 Medicine-Nephrology

CiteScore

0.10

自引率

0.00%

发文量

14180

期刊介绍： Chinese Journal of Urology (monthly) was founded in 1980. It is a publicly issued academic journal supervised by the China Association for Science and Technology and sponsored by the Chinese Medical Association. It mainly publishes original research papers, reviews and comments in this field. This journal mainly reports on the latest scientific research results and clinical diagnosis and treatment experience in the professional field of urology at home and abroad, as well as basic theoretical research results closely related to clinical practice. The journal has columns such as treatises, abstracts of treatises, experimental studies, case reports, experience exchanges, reviews, reviews, lectures, etc. Chinese Journal of Urology has been included in well-known databases such as Peking University Journal (Chinese Journal of Humanities and Social Sciences), CSCD Chinese Science Citation Database Source Journal (including extended version), and also included in American Chemical Abstracts (CA). The journal has been rated as a quality journal by the Association for Science and Technology and as an excellent journal by the Chinese Medical Association.