血液透析患者COVID-19感染的流行及临床表现

Q4 Medicine
A. Kenarkoohi, M. Maleki, B. Ghiasi, Elham Bastani, I. Pakzad, M. Bonyadi, A. Abdoli, S. Falahi
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引用次数: 5

摘要

血液透析(HD)患者感染严重急性呼吸综合征冠状病毒2 (SARS-CoV-2)的风险增加。目的:本研究的目的是评估HD患者SARS-CoV-2感染的患病率和临床症状。患者和方法:这是一项在伊朗Ilam HD中心进行的单中心研究。这项研究包括87名HD患者进行测试。采用实时逆转录聚合酶链反应(rRT-PCR)法确诊SARS-CoV-2感染。结果:约35.63%的HD患者被诊断为COVID-19感染;以男性居多(74.4%)。呼吸困难(58.1%)和咳嗽(45.2%)是HD合并SARS-CoV-2感染患者最常见的症状。糖尿病(16.1%)和高血压(19.4%)是最常共存的内科疾病。约12.9%的患者需要ICU护理。此外,16.1%的患者死亡,全部为男性。结论:本研究显示我们的HD组中COVID-19患病率高,伴有轻度症状。HD患者可能是对COVID-19最敏感和高风险的人群之一,因为他们年龄大、合并症、免疫功能低下、需要频繁就诊,以及HD中心的患者负担过重。应采取预防措施,尽量减少病毒在透析中心的传播。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence and clinical presentation of COVID-19 infection in hemodialysis patients
Introduction: Hemodialysis (HD) patients are at increased risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Objectives: The aim of this study was to evaluate the prevalence and clinical symptoms of SARS-CoV-2 infection in HD patients. Patients and Methods: This is a single-center study conducted at HD center, in Ilam, Iran. The study was included 87 HD patients to be tested. SARS-CoV-2 infection was diagnosed with confirmed test by rRT-PCR (real-time reverse transcription polymerase chain reaction) assay. Results: Around 35.63% of HD patients were diagnosed as COVID-19 infection; most of them were male (74.4%). Dyspnea (58.1%) and cough (45.2%) were the most common symptoms among HD cases with SARS-CoV-2 infection. Diabetes (16.1%) and hypertension (19.4%) were the most coexisting medical illnesses. About 12.9% of patients needed ICU care. Additionally, 16.1% of our patients died, which all of them were male. Conclusion: This study showed a high prevalence of COVID-19 among our HD group, accompanied by mild symptoms. The HD population is probably among the most sensitive and high-risk groups for COVID-19 because of advanced age, comorbidities disease, low-immune function and frequent required visits, and patient overload in HD centers. Preventive measures should be taken in order to minimize the virus transmission in dialysis centers.
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来源期刊
Journal of Nephropathology
Journal of Nephropathology Medicine-Nephrology
CiteScore
1.30
自引率
0.00%
发文量
35
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