{"title":"克罗恩病与系统性红斑狼疮并发狼疮肾炎2例","authors":"M. Somaï","doi":"10.33552/ajgh.2019.01.000510","DOIUrl":null,"url":null,"abstract":"Systemic lupus erythematosus (SLE) is a chronic multisystem inflammatory disease, known as a prototype for autoimmune disease [1,2]. It is usually associated with other autoimmune and dysimmune diseases. Inflammatory bowel disease (IBD) is one of the specific dysimmune diseases of the intestine with extraintestinal involvements and with environmental factors and genetic predisposition [3]. IBD is a chronic recurrent disease comprised of two major phenotypes, Crohn’s disease (CD) and ulcerative colitis [4]. The coexistence of SLE and CD in the same patient is extremely rare (<0.4%) [5]. Even rarer is the association between lupus nephritis (LN) and CD, with only two cases reported to date [6,7]. A review study corroborated that SLE was associated with comorbid CD (OR 2.23) [8]. We communicate herein two cases of patients, ones with SLE who was diagnosed CD colitis and the other with CD who was diagnosed SLE. Case presentation 1","PeriodicalId":72038,"journal":{"name":"Academic journal of gastroenterology & hepatology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2019-08-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Coexistence of Crohn’s Disease and Systemic Lupus Erythematosus with Lupus Nephritis : About Two Cases\",\"authors\":\"M. Somaï\",\"doi\":\"10.33552/ajgh.2019.01.000510\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Systemic lupus erythematosus (SLE) is a chronic multisystem inflammatory disease, known as a prototype for autoimmune disease [1,2]. It is usually associated with other autoimmune and dysimmune diseases. Inflammatory bowel disease (IBD) is one of the specific dysimmune diseases of the intestine with extraintestinal involvements and with environmental factors and genetic predisposition [3]. IBD is a chronic recurrent disease comprised of two major phenotypes, Crohn’s disease (CD) and ulcerative colitis [4]. The coexistence of SLE and CD in the same patient is extremely rare (<0.4%) [5]. Even rarer is the association between lupus nephritis (LN) and CD, with only two cases reported to date [6,7]. A review study corroborated that SLE was associated with comorbid CD (OR 2.23) [8]. We communicate herein two cases of patients, ones with SLE who was diagnosed CD colitis and the other with CD who was diagnosed SLE. Case presentation 1\",\"PeriodicalId\":72038,\"journal\":{\"name\":\"Academic journal of gastroenterology & hepatology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-08-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Academic journal of gastroenterology & hepatology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33552/ajgh.2019.01.000510\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Academic journal of gastroenterology & hepatology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33552/ajgh.2019.01.000510","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Coexistence of Crohn’s Disease and Systemic Lupus Erythematosus with Lupus Nephritis : About Two Cases
Systemic lupus erythematosus (SLE) is a chronic multisystem inflammatory disease, known as a prototype for autoimmune disease [1,2]. It is usually associated with other autoimmune and dysimmune diseases. Inflammatory bowel disease (IBD) is one of the specific dysimmune diseases of the intestine with extraintestinal involvements and with environmental factors and genetic predisposition [3]. IBD is a chronic recurrent disease comprised of two major phenotypes, Crohn’s disease (CD) and ulcerative colitis [4]. The coexistence of SLE and CD in the same patient is extremely rare (<0.4%) [5]. Even rarer is the association between lupus nephritis (LN) and CD, with only two cases reported to date [6,7]. A review study corroborated that SLE was associated with comorbid CD (OR 2.23) [8]. We communicate herein two cases of patients, ones with SLE who was diagnosed CD colitis and the other with CD who was diagnosed SLE. Case presentation 1