M. Drissa (Professor), A. Ayadi (Intern), H. Drissa (Professor)
{"title":"系统性红斑狼疮的超声心动图表现","authors":"M. Drissa (Professor), A. Ayadi (Intern), H. Drissa (Professor)","doi":"10.1016/j.acvdsp.2023.04.041","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p><span>Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by inflammation of multiple organs. The heart may be seriously involved. Aim of study: to investigate the cardiac involvement </span>in patients diagnosed with SLE assessed from an echocardiographic view.</p></div><div><h3>Method</h3><p>We retrospectively reviewed the records of 75 patients with diagnosis of SLE based on the American College of Rheumatology<span> criteria and who were referred to our echocardiography laboratory between 2010 to 2022. All echocardiographic exams were carried by transthoracic way.</span></p></div><div><h3>Results</h3><p>Patients were female in 92% of cases. Mean age was 27.8<!--> <!-->years (16–70<!--> <span><span>years). Echocardiography showed 17 cases (22%) of minim or moderate pericardial effusion, tamponadein 2 cases. Valvularabnormalities were observed in 19 cases (25%), this included thickening of valves in all cases associated to 6 cases of significant </span>mitral regurgitation (></span> <span><span><span>grade 1) and 2 cases of Libman sacks mitral valve </span>endocarditis. However, aortic involvement was noted only in 3 cases resulting in thickening and mild regurgitation. </span>Myocardium<span> was involved in 5 cases (6%) including dilated left ventricular in 3 cases and hypertrophy in 2 cases. High arterial pulmonary hypertension was reported in 4 cases (5%) with mean systolic pulmonary arterial pressure was 59</span></span> <!-->mmHg (38–120<!--> <!-->mmHg).</p></div><div><h3>Conclusion</h3><p>Patients with SLE have an increased risk of cardiac involvement. In agreement with previous reports, our study shows that pericardial effusion is the most frequent cardiac complication of lupus and Valvular involvement in SLE is relatively frequent but the degree of valvular dysfunction is not important. Echocardiography should be used as a screening tool in these patients, including annual echocardiographic screening of asymptomatic individuals with systemic autoimmunity.</p></div>","PeriodicalId":8140,"journal":{"name":"Archives of Cardiovascular Diseases Supplements","volume":null,"pages":null},"PeriodicalIF":18.0000,"publicationDate":"2023-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Echocardiographic findings in systemic lupus erythematosus\",\"authors\":\"M. Drissa (Professor), A. Ayadi (Intern), H. Drissa (Professor)\",\"doi\":\"10.1016/j.acvdsp.2023.04.041\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p><span>Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by inflammation of multiple organs. The heart may be seriously involved. Aim of study: to investigate the cardiac involvement </span>in patients diagnosed with SLE assessed from an echocardiographic view.</p></div><div><h3>Method</h3><p>We retrospectively reviewed the records of 75 patients with diagnosis of SLE based on the American College of Rheumatology<span> criteria and who were referred to our echocardiography laboratory between 2010 to 2022. All echocardiographic exams were carried by transthoracic way.</span></p></div><div><h3>Results</h3><p>Patients were female in 92% of cases. Mean age was 27.8<!--> <!-->years (16–70<!--> <span><span>years). Echocardiography showed 17 cases (22%) of minim or moderate pericardial effusion, tamponadein 2 cases. Valvularabnormalities were observed in 19 cases (25%), this included thickening of valves in all cases associated to 6 cases of significant </span>mitral regurgitation (></span> <span><span><span>grade 1) and 2 cases of Libman sacks mitral valve </span>endocarditis. However, aortic involvement was noted only in 3 cases resulting in thickening and mild regurgitation. </span>Myocardium<span> was involved in 5 cases (6%) including dilated left ventricular in 3 cases and hypertrophy in 2 cases. High arterial pulmonary hypertension was reported in 4 cases (5%) with mean systolic pulmonary arterial pressure was 59</span></span> <!-->mmHg (38–120<!--> <!-->mmHg).</p></div><div><h3>Conclusion</h3><p>Patients with SLE have an increased risk of cardiac involvement. In agreement with previous reports, our study shows that pericardial effusion is the most frequent cardiac complication of lupus and Valvular involvement in SLE is relatively frequent but the degree of valvular dysfunction is not important. Echocardiography should be used as a screening tool in these patients, including annual echocardiographic screening of asymptomatic individuals with systemic autoimmunity.</p></div>\",\"PeriodicalId\":8140,\"journal\":{\"name\":\"Archives of Cardiovascular Diseases Supplements\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":18.0000,\"publicationDate\":\"2023-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Cardiovascular Diseases Supplements\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1878648023001805\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Cardiovascular Diseases Supplements","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1878648023001805","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Echocardiographic findings in systemic lupus erythematosus
Introduction
Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by inflammation of multiple organs. The heart may be seriously involved. Aim of study: to investigate the cardiac involvement in patients diagnosed with SLE assessed from an echocardiographic view.
Method
We retrospectively reviewed the records of 75 patients with diagnosis of SLE based on the American College of Rheumatology criteria and who were referred to our echocardiography laboratory between 2010 to 2022. All echocardiographic exams were carried by transthoracic way.
Results
Patients were female in 92% of cases. Mean age was 27.8 years (16–70 years). Echocardiography showed 17 cases (22%) of minim or moderate pericardial effusion, tamponadein 2 cases. Valvularabnormalities were observed in 19 cases (25%), this included thickening of valves in all cases associated to 6 cases of significant mitral regurgitation (>grade 1) and 2 cases of Libman sacks mitral valve endocarditis. However, aortic involvement was noted only in 3 cases resulting in thickening and mild regurgitation. Myocardium was involved in 5 cases (6%) including dilated left ventricular in 3 cases and hypertrophy in 2 cases. High arterial pulmonary hypertension was reported in 4 cases (5%) with mean systolic pulmonary arterial pressure was 59 mmHg (38–120 mmHg).
Conclusion
Patients with SLE have an increased risk of cardiac involvement. In agreement with previous reports, our study shows that pericardial effusion is the most frequent cardiac complication of lupus and Valvular involvement in SLE is relatively frequent but the degree of valvular dysfunction is not important. Echocardiography should be used as a screening tool in these patients, including annual echocardiographic screening of asymptomatic individuals with systemic autoimmunity.
期刊介绍:
Archives of Cardiovascular Diseases Supplements is the official journal of the French Society of Cardiology. The journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles, editorials, and Images in cardiovascular medicine. The topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Additionally, Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.