系统性红斑狼疮的超声心动图表现

IF 18 Q4 Medicine
M. Drissa (Professor), A. Ayadi (Intern), H. Drissa (Professor)
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引用次数: 0

摘要

系统性红斑狼疮(SLE)是一种以多器官炎症为特征的自身免疫性疾病。心脏可能会受到严重影响。研究目的:探讨超声心动图评价SLE患者心脏受累情况。方法回顾性分析2010年至2022年间,根据美国风湿病学会标准诊断为SLE并转诊至超声心动图实验室的75例患者。超声心动图检查均经胸行。结果92%的患者为女性。平均年龄27.8岁(16 ~ 70岁)。超声心动图显示轻度或中度心包积液17例(22%),心包填塞2例。19例(25%)患者瓣膜异常,包括6例明显二尖瓣返流患者瓣膜增厚(>1级)和2例Libman袋状二尖瓣心内膜炎。然而,主动脉受累仅3例,导致增厚和轻度反流。累及心肌5例(6%),其中左心室扩张3例,肥厚2例。高动脉性肺动脉高压4例(5%),平均肺动脉收缩压59 mmHg (38 ~ 120 mmHg)。结论SLE患者心脏受累风险增加。与以往的报道一致,我们的研究表明心包积液是狼疮最常见的心脏并发症,SLE的瓣膜受累相对频繁,但瓣膜功能障碍的程度并不重要。超声心动图应作为这些患者的筛查工具,包括每年超声心动图筛查无症状的全身自身免疫个体。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Echocardiographic findings in systemic lupus erythematosus

Introduction

Systemic lupus erythematosus (SLE) is an autoimmune disease characterized by inflammation of multiple organs. The heart may be seriously involved. Aim of study: to investigate the cardiac involvement in patients diagnosed with SLE assessed from an echocardiographic view.

Method

We retrospectively reviewed the records of 75 patients with diagnosis of SLE based on the American College of Rheumatology criteria and who were referred to our echocardiography laboratory between 2010 to 2022. All echocardiographic exams were carried by transthoracic way.

Results

Patients were female in 92% of cases. Mean age was 27.8 years (16–70 years). Echocardiography showed 17 cases (22%) of minim or moderate pericardial effusion, tamponadein 2 cases. Valvularabnormalities were observed in 19 cases (25%), this included thickening of valves in all cases associated to 6 cases of significant mitral regurgitation (> grade 1) and 2 cases of Libman sacks mitral valve endocarditis. However, aortic involvement was noted only in 3 cases resulting in thickening and mild regurgitation. Myocardium was involved in 5 cases (6%) including dilated left ventricular in 3 cases and hypertrophy in 2 cases. High arterial pulmonary hypertension was reported in 4 cases (5%) with mean systolic pulmonary arterial pressure was 59 mmHg (38–120 mmHg).

Conclusion

Patients with SLE have an increased risk of cardiac involvement. In agreement with previous reports, our study shows that pericardial effusion is the most frequent cardiac complication of lupus and Valvular involvement in SLE is relatively frequent but the degree of valvular dysfunction is not important. Echocardiography should be used as a screening tool in these patients, including annual echocardiographic screening of asymptomatic individuals with systemic autoimmunity.

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来源期刊
Archives of Cardiovascular Diseases Supplements
Archives of Cardiovascular Diseases Supplements CARDIAC & CARDIOVASCULAR SYSTEMS-
自引率
0.00%
发文量
508
期刊介绍: Archives of Cardiovascular Diseases Supplements is the official journal of the French Society of Cardiology. The journal publishes original peer-reviewed clinical and research articles, epidemiological studies, new methodological clinical approaches, review articles, editorials, and Images in cardiovascular medicine. The topics covered include coronary artery and valve diseases, interventional and pediatric cardiology, cardiovascular surgery, cardiomyopathy and heart failure, arrhythmias and stimulation, cardiovascular imaging, vascular medicine and hypertension, epidemiology and risk factors, and large multicenter studies. Additionally, Archives of Cardiovascular Diseases also publishes abstracts of papers presented at the annual sessions of the Journées Européennes de la Société Française de Cardiologie and the guidelines edited by the French Society of Cardiology.
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