ACTH4-10pro8-gly9-pro10对大鼠脊髓损伤中丙二醛和f2 -异前列腺素15(S)-8-iso-PGF2a表达的影响

Q4 Medicine

Gaceta Medica de Caracas Pub Date : 2023-08-23 DOI:10.47307/gmc.2023.131.s4.15

Rifqi Aulia Destiansyah

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引用次数: 0

摘要

背景：脊髓损伤（SCI）是主要由创伤引起的脊髓损伤，导致主要的运动、感觉和自主神经功能障碍。本实验研究旨在评估轻度和重度压迫性损伤大鼠服用ACTH4-10Pro8-Gly9-Pro10对丙二醛和F2-异丙酮15（S）-8-异-PGF2α水平的影响。方法：对27例受试者进行轻度和重度脊髓压迫。他们被分为三组，对照组包括受伤后3和6小时。

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Effect of ACTH4-10pro8-gly9-pro10 on malondialdehyde and F2-isoprostane 15(S)-8-iso-PGF2a expression in rat spinal cord injury

Background: Spinal cord injury (SCI) is damage to the spinal cord caused mainly by trauma resulting in major motor, sensory, and autonomic dysfunctions. This experimental study aims to assess the effect of ACTH4-10Pro8-Gly9-Pro10 administration in rats with mild and severe compression injuries on the levels of malondialdehyde and F2-isoprostane 15(S)-8-iso-PGF2α levels. Methods: Mild and severe spinal cord compression was performed on 27 subjects. They were divided into three groups of samples with control included, 3 and 6 h after the injury.

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来源期刊

Gaceta Medica de Caracas Medicine-Medicine (all)

CiteScore

0.30

自引率

0.00%

发文量

160

期刊介绍： Gaceta Médica de Caracas Órgano de la Academia Nacional de Medicina y del Congreso Venezolano de Ciencias Médicas Salud Fundada el 13 de marzo de 1893 Trimestral GMC