Arad地区SARS_Cov_2感染的流行病学、临床及解剖病理分析

IF 0.4 4区 医学 Q4 Medicine
I. Olariu, C. Precup, M. Mot, V. Toma, I. Toma, D. Negru, F. Sándor, L. Bran, S. Laitin, T. Olariu
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引用次数: 0

摘要

目标。2020年彻底改变了罗马尼亚医院患者的治疗方法,重症监护病房(icu)有时超负荷使用;我们的目标是确定2020年在阿拉德援助的Covid - 19患者的成功率。材料和方法。对2020年5月28日至25日住院的450例Covid - 19患者的人口学特征、症状、合并症、住院时间、治疗方案和成功率进行分析。结果。患者年龄从19岁到99岁不等,女性平均为56.75岁,男性平均为56.11岁,女性平均住院12天,男性平均住院17天,严重形式的风险也高于女性(RR 1.4483, 95% CI 1.0012-2.095, P = 0.0493);男性的比值比OR增加,但未进行统计学验证(OR 1.5023, 95% CI 10.9175-2.46, P = 0.1057)。高血压合并糖尿病患者死亡率增高(OR: 26.6049, P = 0.0353)。仅5.55%的病例(n = 25)进行了相关细菌药物的分离,但抗生素方案的靶向性为54.66% (n = 246)。与2019年相比,尽管出院患者和标本数量有所减少,但2020年该医院循环菌株的多药耐药情况有所增加。结论。在没有证实继发性细菌感染的情况下,对Covid - 19进行抗生素治疗是不合理的,这导致了多药耐药细菌菌株的选择增加,这是一个已经确定的事实。版权所有©2022罗马尼亚法律医学协会。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Epidemiological, Clinical and Anatomopathological Analysis in SARS_Cov_2 Infection in Arad
Objective. The year 2020 radically changed the therapeutic approach in patients of Romanian hospitals, and intensive care units (ICUs) were sometimes used over capacity;our goal was to establish the success rate in Covid 19 patients assisted in 2020 in Arad. Material and methods. Were analyzed 450 Covid 19 cases hospitalized between 28.03-25.05.2020, regarding the demographic characteristics, symptomatology, comorbidities, hospitalisation length, treatment regimens and success rates. Results. Patients ranged in age from 19 to 99 years, with a mean of 56.75 for women and 56.11 for men, with hospitalization averaging 12 days for women and 17 days for men, who had also a higher risk for severe forms compared to women (RR 1.4483, 95% CI 1.0012-2.095, P = 0.0493);Odds ratio OR in men was increased but without statistical validation (OR 1.5023, 95% CI 10.9175-2.46, P = 0.1057). The death rate was increased in cases with hypertension associated to diabetes (OR 26.6049, P = 0.0353). Isolation of associated bacterial agents was performed in only 5.55% of cases (n = 25) but antibiotic regimens targeted 54.66% (n = 246) of cases. Multidrug resistance of circulating strains in 2020 in this hospital has increased despite the decrease in the number of patients discharged and specimens, compared to 2019. Conclusions. Antibiotic therapy in Covid 19 is not justified in the absence of a proven secondary bacterial infection, contributing to the increase in the selection of multidrug resistant bacterial strains, which is a fact already ascertained. Copyright © 2022 Romanian Society of Legal Medicine.
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来源期刊
CiteScore
0.50
自引率
25.00%
发文量
0
审稿时长
6-12 weeks
期刊介绍: The Romanian Journal of Legal Medicine, the official publication of the Romanian Legal Medicine Society, is devoted to the publication of the original investigations, observations, scholarly inquiries and reviews in the various branches of the forensic sciences. These include forensic pathology and histochemistry, clinical forensic medicine, medical malpractice, traffic medicine, chemistry, biochemistry, thanatochemistry, clinical and forensic toxicology, alcohology, biology (including the identification of hairs and fibres), the physical sciences, firearms, and document examination, physical anthropology, serology, forensic genetics and paternity (with special emphasis on recent advances in DNA technology and PCR), forensic psychiatry and behavioral sciences, forensic odontology, law and ethics, history of forensic sciences. RJLM also includes similar submissions dealing with forensic-oriented aspects of the social science and the area where science and medicine interact with the law.
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