基于分形角的子宫肌电信号对足月妊娠的鉴别

P. Vardhini, Non-Invasive Imaging, S. Ramakrishnan
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引用次数: 1

摘要

子宫肌电图(uEMG)是一种从腹部表面定量测量子宫活动的非侵入性技术。在这项工作中,试图使用自适应分形分析(AFA)来研究足月(胎龄>37周)uEMG信号。为此,考虑在第二和第三三聚体中获得的信号并进行AFA。基于卡方统计量、斜率标准误差和确定系数,计算波动函数并识别相应的线性标度区域。从多个尺度区域(即分形间角和短期和长期分形角)提取基于角度的特征,并用于进一步分析。所获得的结果表明,AFA方法可以表征不同胎龄的Term信号。两组的所有特征均显示出显著差异(p<0.05)。特征值表明,与妊娠中期信号相比,妊娠晚期信号具有更相关、更平稳的波动。这归因于分娩临近时子宫收缩的协调性增强。因此,所提出的基于自适应角度的分形特征可能是分析与足月妊娠相关的肌肉收缩的潜在生物标志物。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
FRACTAL ANGLE BASED DIFFERENTIATION OF TERM PREGNANCIES USING UTERINE ELECTROMYOGRAPHIC SIGNALS
Uterine Electromyography (uEMG) is a non-invasive technique that provides quantitative measure of uterine activity from the abdominal surface. In this work, an attempt has been made to investigate Term (gestational age > 37 weeks) uEMG signals using Adaptive Fractal Analysis (AFA). For this, the signals obtained in second and third trimesters are considered and subjected to AFA. The fluctuation function is computed and the corresponding linear scaling regions are identified based on Chi-square statistic, standard error of slope, and coefficient of determination. Angle-based features from multiple scaling regions namely, inter-fractal angle and, short- and long-term fractal angles are extracted and are used for further analysis. The obtained results demonstrates that AFA approach can characterize the Term signals during varied gestational ages. All features show significant differences (p < 0.05) in both groups. Feature values suggest that the third trimester signals possess more correlated and smoother fluctuations when compared to second trimester signals. This is attributed to the increased coordination of uterine contractions as delivery approaches. Hence, it appears that the proposed adaptive angle-based fractal features could be potential biomarkers in analyzing the muscle contractions associated with Term pregnancies.
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