粪便抗原试验与尿素呼气试验诊断苏莱曼尼亚市儿童幽门螺杆菌感染的比较

A. Hassan, Hamza Ali Faraj, H. Mohammad
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引用次数: 1

摘要

目的:由于儿童幽门螺杆菌感染的发病率不断增加,了解无创检测中哪种诊断检测更准确、更特异、更敏感是很重要的。方法:45名儿童接受了同一位儿科胃肠病学家的口服胃十二指肠镜检查,进行尿素呼气测试(UBT)和粪便抗原测试(SAT);他们的数据通过回顾性研究(2013-2019)进行了分析,以使用活检发现(组织病理学发现)作为诊断的验证工具,对UBT和SAT(特异性、敏感性和准确性)进行比较。根据患者的临床表现选择患者,本研究的纳入标准为:(儿科年龄组,有幽门螺杆菌感染的临床表现,病史、临床检查和测试的完整信息)。排除信息不完整的患者。结果:男性(75.56%)比女性(24.44%)更常见,腹痛(53.3%)是主要表现,其次是吐血(20%),UBT比其他测试更受人口统计学特征的影响,UBT与活检结果有统计学显著相关性,也比SAT更准确、更敏感,但它们具有相同的阳性预测值和相同的特异性。结论:UBT优于SAT,尤其适用于6岁以上儿童。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Comparison between stool antigen test and urea breath test for diagnosing of Helicobacter pylori infection among Children in Sulaymaniyah City
Objectives: Due to increasing incidence of Helicobacter pylori infections among children, it is important to understand which diagnostic test among the noninvasive tests is more accurate, specific, and sensitive. Methodology: Forty-five children who underwent osophagogastroduodenoscopy by the same pediatric gastroenterologist, with Urea Breath Test (UBT) and Stool Antigen Test (SAT); their data were analyzed by retrospective study (2013–2019) to make a comparison between UBT and SAT (Specificity, Sensitivity, and Accuracy) using biopsy finding (histopathological finding) as confirmatory tool for diagnosis. Patients were selected according to their clinical presentations and inclusion criteria in this study are: (pediatric age group, have clinical presentation of H. pylori infection, full information in history, clinical examination, and tests). Patients with incomplete information were excluded. Results: Male (75.56%) more common than female (24.44%), abdominal pain (53.3%) is the major presentation followed by hematemesis (20%), UBT is more influenced by demographic characteristics than other tests, UBT has a statistical significant correlation with result of biopsy, also it is more accurate and more sensitive than SAT, but they share same positive predictive value and same specificity. Conclusions: UBT more preferable than SAT specially in children above 6-year-old.
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