Zeeshan Khan, S. Khaleeq, A. ur Rehman, Aasam Maan, Umer Farooq, Amjad Nadeem
{"title":"扑热息痛与伏特栓剂治疗妇科手术后疼痛的比较","authors":"Zeeshan Khan, S. Khaleeq, A. ur Rehman, Aasam Maan, Umer Farooq, Amjad Nadeem","doi":"10.51273/esc21.2517217","DOIUrl":null,"url":null,"abstract":"Objective: To compare intravenous paracetamol vs Voltral (Diclofenac) suppositories for post operative pain in gynaecological procedures. Methods: This was a non randomized controlled trial that was carried out at Department of Anaesthesiology, Sheikh Zayed Hospital, Rahim Yar Khan during 01-07-2019 to 31-12-2019 in which all female cases with age range of 20 to 60 year undergoing any gynaecological surgery requiring general anaesthesia were included. The cases were divided into two equal groups and anesthesia was offered in standard doses. Just before reversal the cases in group Awere given intravenous paracetamol in a dose of 1 gm stat and then at 8-hour interval and those in group B were offered diclofenac suppositories in a dose of 50 mg twice a day, 12 hours apart. The pain was assessed at 4,8,12 and 24 hours and was labelled on visual analogue scale (VAS). Results: In this study there were 62 cases (31 in each group). The mean age in group A and B was 45.41±10.21 vs 48.12±11.13 years with p= 0.47. Mean duration of surgery in both groups was 57.51±15.23 vs53.11±14.79 minutes with p= 0.81. There was no significant difference in mean pain score at 4 and 8 hours with p= 0.91 and 0.81 respectively in group A and B. Mean pain score was 4.43±1.67 vs 3.21±1.09 with p= 0.01 at 12 and 4.57±1.71 vs 3.34±1.27 at 24 hours in group A and B with p values of 0.01 each. Mean time taken for rescue analgesia was 9.13±2.11 in group Aand 13.11±1.23 hours in group B with p= 0.001. Conclusion: Voltral (Diclofenac sodium) suppositories are better than paracetamol infusion in controlling pain after gynecological surgeries and this difference is significantly better at 12 and 24 hours. Key words: Gynaecological surgery, Pain, Paracetamol, Voltral suppository How to cite: Khan Z., Khaleeq S., Rehman Ur A., Maan A., Farooq U. Nadeem A. Comparison Between Paracetamol Vs Voltral Suppositories for Post-Operative Pain in Gynaecological Procedures. Esculapio 2021;17(02):191-194.","PeriodicalId":11923,"journal":{"name":"Esculapio","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2021-07-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Comparison Between Paracetamol Vs Voltral Suppositories For Post Operative Pain In Gynaecological Procedure\",\"authors\":\"Zeeshan Khan, S. Khaleeq, A. ur Rehman, Aasam Maan, Umer Farooq, Amjad Nadeem\",\"doi\":\"10.51273/esc21.2517217\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Objective: To compare intravenous paracetamol vs Voltral (Diclofenac) suppositories for post operative pain in gynaecological procedures. Methods: This was a non randomized controlled trial that was carried out at Department of Anaesthesiology, Sheikh Zayed Hospital, Rahim Yar Khan during 01-07-2019 to 31-12-2019 in which all female cases with age range of 20 to 60 year undergoing any gynaecological surgery requiring general anaesthesia were included. The cases were divided into two equal groups and anesthesia was offered in standard doses. Just before reversal the cases in group Awere given intravenous paracetamol in a dose of 1 gm stat and then at 8-hour interval and those in group B were offered diclofenac suppositories in a dose of 50 mg twice a day, 12 hours apart. The pain was assessed at 4,8,12 and 24 hours and was labelled on visual analogue scale (VAS). Results: In this study there were 62 cases (31 in each group). The mean age in group A and B was 45.41±10.21 vs 48.12±11.13 years with p= 0.47. Mean duration of surgery in both groups was 57.51±15.23 vs53.11±14.79 minutes with p= 0.81. There was no significant difference in mean pain score at 4 and 8 hours with p= 0.91 and 0.81 respectively in group A and B. Mean pain score was 4.43±1.67 vs 3.21±1.09 with p= 0.01 at 12 and 4.57±1.71 vs 3.34±1.27 at 24 hours in group A and B with p values of 0.01 each. Mean time taken for rescue analgesia was 9.13±2.11 in group Aand 13.11±1.23 hours in group B with p= 0.001. Conclusion: Voltral (Diclofenac sodium) suppositories are better than paracetamol infusion in controlling pain after gynecological surgeries and this difference is significantly better at 12 and 24 hours. Key words: Gynaecological surgery, Pain, Paracetamol, Voltral suppository How to cite: Khan Z., Khaleeq S., Rehman Ur A., Maan A., Farooq U. Nadeem A. Comparison Between Paracetamol Vs Voltral Suppositories for Post-Operative Pain in Gynaecological Procedures. 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引用次数: 0
摘要
目的：比较静脉注射对乙酰氨基酚栓剂与复方双氯芬酸栓剂治疗妇科手术后疼痛的疗效。方法：这是一项非随机对照试验，于2019年7月1日至2019年12月31日在拉希姆·亚尔汗谢赫·扎耶德医院麻醉科进行，其中包括所有年龄在20至60岁之间接受任何需要全身麻醉的妇科手术的女性病例。将这些病例分为两组，并以标准剂量进行麻醉。就在逆转之前，a组的病例静脉注射1克的扑热息痛，然后间隔8小时，B组的病例每天两次，间隔12小时，每次50毫克的双氯芬酸栓剂。在4、8、12和24小时对疼痛进行评估，并在视觉模拟评分（VAS）上进行标记。结果：本研究共有62例（每组31例）。A组和B组的平均年龄分别为45.41±10.21和48.12±11.13岁，p=0.047。两组的平均手术时间分别为57.51±15.23和53.11±14.79分钟，p=0.81。A组和B组在4小时和8小时的平均疼痛评分分别为0.91和0.81，无显著差异。A组和B组在12小时和24小时的平均痛苦评分分别为4.43±1.67和3.21±1.09，p值分别为0.01和4.57±1.71和3.34±1.27，p值均为0.01。A组的平均抢救镇痛时间为9.13±2.11小时，B组为13.11±1.23小时，p=0.001。结论：双氯芬酸钠栓剂对妇科手术后疼痛的控制效果优于扑热息痛，且在12小时和24小时时差异显著。关键词：妇科手术，疼痛，扑热息痛，伏曲栓如何引用：Khan Z.，Khaleeq S.，Rehman Ur A.，Maan A.，Farooq U.Nadeem A.扑热息醇与伏曲栓在妇科手术中治疗术后疼痛的比较。Esculapio 2021；17（02）：191-194。
Comparison Between Paracetamol Vs Voltral Suppositories For Post Operative Pain In Gynaecological Procedure
Objective: To compare intravenous paracetamol vs Voltral (Diclofenac) suppositories for post operative pain in gynaecological procedures. Methods: This was a non randomized controlled trial that was carried out at Department of Anaesthesiology, Sheikh Zayed Hospital, Rahim Yar Khan during 01-07-2019 to 31-12-2019 in which all female cases with age range of 20 to 60 year undergoing any gynaecological surgery requiring general anaesthesia were included. The cases were divided into two equal groups and anesthesia was offered in standard doses. Just before reversal the cases in group Awere given intravenous paracetamol in a dose of 1 gm stat and then at 8-hour interval and those in group B were offered diclofenac suppositories in a dose of 50 mg twice a day, 12 hours apart. The pain was assessed at 4,8,12 and 24 hours and was labelled on visual analogue scale (VAS). Results: In this study there were 62 cases (31 in each group). The mean age in group A and B was 45.41±10.21 vs 48.12±11.13 years with p= 0.47. Mean duration of surgery in both groups was 57.51±15.23 vs53.11±14.79 minutes with p= 0.81. There was no significant difference in mean pain score at 4 and 8 hours with p= 0.91 and 0.81 respectively in group A and B. Mean pain score was 4.43±1.67 vs 3.21±1.09 with p= 0.01 at 12 and 4.57±1.71 vs 3.34±1.27 at 24 hours in group A and B with p values of 0.01 each. Mean time taken for rescue analgesia was 9.13±2.11 in group Aand 13.11±1.23 hours in group B with p= 0.001. Conclusion: Voltral (Diclofenac sodium) suppositories are better than paracetamol infusion in controlling pain after gynecological surgeries and this difference is significantly better at 12 and 24 hours. Key words: Gynaecological surgery, Pain, Paracetamol, Voltral suppository How to cite: Khan Z., Khaleeq S., Rehman Ur A., Maan A., Farooq U. Nadeem A. Comparison Between Paracetamol Vs Voltral Suppositories for Post-Operative Pain in Gynaecological Procedures. Esculapio 2021;17(02):191-194.
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