{"title":"反相高效液相色谱法测定阿莫西林残留量的建立与验证及在NICOMAC涂布机上的应用","authors":"H. Mem, Mohamed Ma","doi":"10.15406/JAPLR.2018.07.00287","DOIUrl":null,"url":null,"abstract":"AMO, is a semi-synthetic penicillin antibacterial drug derived from a fermentation product. Chemically, it is (2S,5R,6R)-6-[[(2R)2-Amino-2-(4-hydroxyphenyl) acetyl] amino]-3,3-dimethyl-7-oxo-4thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid trihydrate having a molecular formula of C16H19N3O5S.3H2O and its molecular weight is 419.4. AMO is a crystalline powder with white or almost white appearance. It is slightly soluble in water, very slightly soluble in ethanol (96%), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides.","PeriodicalId":92063,"journal":{"name":"Journal of analytical & pharmaceutical research","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-10-18","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"8","resultStr":"{\"title\":\"Development and validation of RP-HPLC method for determination of amoxicillin residues and application to NICOMAC coating machine\",\"authors\":\"H. Mem, Mohamed Ma\",\"doi\":\"10.15406/JAPLR.2018.07.00287\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"AMO, is a semi-synthetic penicillin antibacterial drug derived from a fermentation product. Chemically, it is (2S,5R,6R)-6-[[(2R)2-Amino-2-(4-hydroxyphenyl) acetyl] amino]-3,3-dimethyl-7-oxo-4thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid trihydrate having a molecular formula of C16H19N3O5S.3H2O and its molecular weight is 419.4. AMO is a crystalline powder with white or almost white appearance. It is slightly soluble in water, very slightly soluble in ethanol (96%), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides.\",\"PeriodicalId\":92063,\"journal\":{\"name\":\"Journal of analytical & pharmaceutical research\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-10-18\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"8\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of analytical & pharmaceutical research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.15406/JAPLR.2018.07.00287\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of analytical & pharmaceutical research","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.15406/JAPLR.2018.07.00287","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Development and validation of RP-HPLC method for determination of amoxicillin residues and application to NICOMAC coating machine
AMO, is a semi-synthetic penicillin antibacterial drug derived from a fermentation product. Chemically, it is (2S,5R,6R)-6-[[(2R)2-Amino-2-(4-hydroxyphenyl) acetyl] amino]-3,3-dimethyl-7-oxo-4thia-1-azabicyclo [3.2.0] heptane-2-carboxylic acid trihydrate having a molecular formula of C16H19N3O5S.3H2O and its molecular weight is 419.4. AMO is a crystalline powder with white or almost white appearance. It is slightly soluble in water, very slightly soluble in ethanol (96%), practically insoluble in fatty oils. It dissolves in dilute acids and dilute solutions of alkali hydroxides.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
