拉曼光谱及其在活细胞和组织分析中的应用

IF 0.3 Q4 SPECTROSCOPY

Biomedical Spectroscopy and Imaging Pub Date : 2019-01-24 DOI:10.3233/BSI-180184

H. Sato, M. Ishigaki, Akinori Taketani, B. Andriana

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引用次数: 8

摘要

随着生命科学领域的研究进展，对能够使我们研究完整细胞和组织的新技术的需求越来越大。基于经验数据的生物定量分析和数学建模有助于将分子生物学与计算生物学等新领域联系起来。拉曼光谱被认为是一种可能的方法，通过它我们可以无创地观察活体。这可以提高医学和健康领域的研究质量，并将在很大程度上为未来的社会做出贡献。本文介绍了一些基于拉曼光谱的技术，并评价了它们在完整活体样品中的应用。

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Raman spectroscopy and its use for live cell and tissue analysis

As research progresses in the field of life sciences, there is an increased demand for new technologies that can allow us to study intact cells and tissues. The quantitative analysis and mathematical modeling of living things based on empirical data is useful for connecting molecular biology to new areas, such as computational biology. Raman spectroscopy is regarded as one of the possible methods by which we can observe living organisms in a noninvasive manner. This could improve the quality of research in the field of medicine and health and will largely contribute to society in the future. The present review introduces some techniques based on Raman spectroscopy and evaluates their applications in intact live samples.

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来源期刊

Biomedical Spectroscopy and Imaging SPECTROSCOPY-

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期刊介绍： Biomedical Spectroscopy and Imaging (BSI) is a multidisciplinary journal devoted to the timely publication of basic and applied research that uses spectroscopic and imaging techniques in different areas of life science including biology, biochemistry, biotechnology, bionanotechnology, environmental science, food science, pharmaceutical science, physiology and medicine. Scientists are encouraged to submit their work for publication in the form of original articles, brief communications, rapid communications, reviews and mini-reviews. Techniques covered include, but are not limited, to the following: • Vibrational Spectroscopy (Infrared, Raman, Teraherz) • Circular Dichroism Spectroscopy • Magnetic Resonance Spectroscopy (NMR, ESR) • UV-vis Spectroscopy • Mössbauer Spectroscopy • X-ray Spectroscopy (Absorption, Emission, Photoelectron, Fluorescence) • Neutron Spectroscopy • Mass Spectroscopy • Fluorescence Spectroscopy • X-ray and Neutron Scattering • Differential Scanning Calorimetry • Atomic Force Microscopy • Surface Plasmon Resonance • Magnetic Resonance Imaging • X-ray Imaging • Electron Imaging • Neutron Imaging • Raman Imaging • Infrared Imaging • Terahertz Imaging • Fluorescence Imaging • Near-infrared spectroscopy.