{"title":"有机合成中六组分和伪六组分反应的展望——兼论绿色化学的几个方面","authors":"Fatemeh Molaei Yielzoleh, Kobra Nikoofar","doi":"10.2174/2213346107999201111201105","DOIUrl":null,"url":null,"abstract":"\n\nIn this review, we focused on the six- and pseudo-six-component transformations in organic\nsyntheses as a class of important and applicable MCRs. Although the MCRs usage in recent\nyears is enhanced the reports for more than five-component MCRs are still rare. In some cases,\nthese kinds of MCRs are the combination of some tandem named reactions that generated a union\nMCR. Preparation of multi-functionalized heterocycles, prevention of intermediate separation, reaction\nprogressing in a one-pot continuous manner, elevated total yield, high atom economy, and\npreparation of potent bioactive multi-cycles hetero-organics via the construction of several new\nbonds are some highlighted features of MCRs. In this article, we classified the mentioned sixcomponent\nreactions based on reaction media. Another subdivision is applied based on thermal\nenergy usage or ambient temperature. In fact, two aspects of the green chemistry rules have been\ndiscussed.\n","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2020-11-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"2","resultStr":"{\"title\":\"An Outlook to Six- and Pseudo Six-component Reactions in Organic Synthesis with a Glance at Some Aspects of Green Chemistry\",\"authors\":\"Fatemeh Molaei Yielzoleh, Kobra Nikoofar\",\"doi\":\"10.2174/2213346107999201111201105\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"\\n\\nIn this review, we focused on the six- and pseudo-six-component transformations in organic\\nsyntheses as a class of important and applicable MCRs. Although the MCRs usage in recent\\nyears is enhanced the reports for more than five-component MCRs are still rare. In some cases,\\nthese kinds of MCRs are the combination of some tandem named reactions that generated a union\\nMCR. Preparation of multi-functionalized heterocycles, prevention of intermediate separation, reaction\\nprogressing in a one-pot continuous manner, elevated total yield, high atom economy, and\\npreparation of potent bioactive multi-cycles hetero-organics via the construction of several new\\nbonds are some highlighted features of MCRs. In this article, we classified the mentioned sixcomponent\\nreactions based on reaction media. Another subdivision is applied based on thermal\\nenergy usage or ambient temperature. In fact, two aspects of the green chemistry rules have been\\ndiscussed.\\n\",\"PeriodicalId\":10856,\"journal\":{\"name\":\"Current Green Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2020-11-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Green Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/2213346107999201111201105\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Green Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2213346107999201111201105","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
An Outlook to Six- and Pseudo Six-component Reactions in Organic Synthesis with a Glance at Some Aspects of Green Chemistry
In this review, we focused on the six- and pseudo-six-component transformations in organic
syntheses as a class of important and applicable MCRs. Although the MCRs usage in recent
years is enhanced the reports for more than five-component MCRs are still rare. In some cases,
these kinds of MCRs are the combination of some tandem named reactions that generated a union
MCR. Preparation of multi-functionalized heterocycles, prevention of intermediate separation, reaction
progressing in a one-pot continuous manner, elevated total yield, high atom economy, and
preparation of potent bioactive multi-cycles hetero-organics via the construction of several new
bonds are some highlighted features of MCRs. In this article, we classified the mentioned sixcomponent
reactions based on reaction media. Another subdivision is applied based on thermal
energy usage or ambient temperature. In fact, two aspects of the green chemistry rules have been
discussed.