二氯甲烷注射液1例报告

Asia Pacific Journal of Medical Toxicology Pub Date : 2018-09-01 DOI:10.22038/APJMT.2018.11981

Kitisak Sanprasert, Thunyaporn Tangtrongchitr, Nat Krairojananan

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引用次数: 2

摘要

背景：二氯甲烷（一种氯化烃）通常用作溶剂。据报道，职业接触导致二氯甲烷中毒，二氯甲烷中毒的常见途径是摄入和吸入。病例介绍：我们描述了一例51岁的男子，他接受了二氯甲烷皮下注射，前臂出现局部伤口坏死，但羧基血红蛋白水平正常。讨论：二氯甲烷的腐蚀性导致其伤口形成静脉血栓，可能阻止二氯甲烷的全身吸收，导致肝脏将二氯甲烷转化为一氧化碳的减少。结论：在皮下注射二氯甲烷的患者中，症状治疗和CO生成监测仍然是主要的治疗方法。

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Dichloromethane Injection: Case Report

Background: Dichloromethane (a chlorinated hydrocarbon) is normally used as a solvent. Dichloromethane poisoning has been reported from occupational exposure and the common routes of dichloromethane poisoning are ingestion and inhalation. Case presentation: We described a case of 51-year-old man who received subcutaneous injection of dichloromethane and presented with local wound necrosis at his forearm, but carboxyhemoglobin levels were normal. Discussion: The corrosive property of dichloromethane result in venous thrombosis formation at his wound that might prevent systemic absorption of dichloromethane leads to reduced hepatic converted dichloromethane to the carbon monoxide. Conclusion: Symptomatic treatment and monitoring of CO production remain the mainstay in the treatment of patients with subcutaneous injection of dichloromethane.

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来源期刊

Asia Pacific Journal of Medical Toxicology

自引率

0.00%

发文量

审稿时长

12 weeks

期刊介绍： Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.