零年代早期-治疗目标

IF 0.4 Q4 ENDOCRINOLOGY & METABOLISM
B. Ryder
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引用次数: 0

摘要

胰岛素发现80年后的20世纪初胰岛素发现80周年后的20年代初,也许可以被称为“靶向治疗”时代。英国前瞻性糖尿病研究(UKPDS),如Rury Holman教授在本补充文章中所述,1表明,尽管强化治疗组的微血管并发症有所减少,但无论患者是在强化治疗组还是常规治疗组,HbA1c都会随着β细胞的不断衰竭而不断上升(图1a)。研究还表明,HbA1c越低,发生微血管事件的可能性就越小(图1b)。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
early noughties - Treating to Target
80 years after the discovery of insulin, the early noughties The era 80 years after the discovery of insulin, the early noughties, could perhaps be labelled the “Treat to Target” era. The United Kingdom Prospective Diabetes Study (UKPDS), as described elsewhere in this supplement by Professor Rury Holman,1 showed that whilst the microvascular complications were reduced in the intensive arm, the HbA1c relentlessly rose as beta cells relentlessly failed (Figure 1a) no matter whether patients were in the intensive or conventional treatment arm. The study also showed that the lower the HbA1c the less likely there are to be microvascular events (Figure 1b).
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来源期刊
British Journal of Diabetes
British Journal of Diabetes ENDOCRINOLOGY & METABOLISM-
自引率
16.70%
发文量
15
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