应用磷酸丙烯和加玛韦控制猫慢性冠状病毒感染

S. Savoyskaya, I. Ogorodnikova, T. Kozhevnikova
{"title":"应用磷酸丙烯和加玛韦控制猫慢性冠状病毒感染","authors":"S. Savoyskaya, I. Ogorodnikova, T. Kozhevnikova","doi":"10.30917/ATT-VK-1814-9588-2021-3-13","DOIUrl":null,"url":null,"abstract":"Feline enteropathogenic coronavirus affects the intestinal epithelium and causes inflammation of the intestinal mucosa in cats. In adult cats, the infection is usually asymptomatic, but the constant circulation of the coronavirus in the feline population can increase the likelihood of mutation leading to appearance of the virulent strain of the virus that cause feline infectious peritonitis - a deadly disease that develops in 5-10% of cats carrying the coronavirus. The aim of this work was to study the effect of the drugs Phosprenyl and Gamavit on the course of coronavirus infection in cats. A total of 29 cats were monitored. The diagnosis was confirmed by the detection of antibodies by the IHA method, as well as by ultrasound examination of the abdominal organs. Prescribed treatment: Phosprenyl per os, 1 ml , twice a day, course 2-4 months; Gamavit 1 time a day, s/c, course 10 days, with a repeated course after 3 weeks; 3-4 times. As symptomatic therapy, drugs were used to improve the condition of the stool. At the end of treatment, symptoms of gastrointestinal tract damage disappeared in all patients. If before the start of treatment, most patients showed signs of anemia (a decrease in the number of red blood cells and hemoglobin levels), leukocytosis with a predominance of segmented neutrophils, characteristic of infectious and inflammatory processes, and increased ESR, then at the end of therapy, these indicators were completely normalized. Thus, long-term therapy with the use of Phosprenyl and Gamavit helps to control the course of coronavirus infection in cats, prevent its exacerbation and transition to a highly lethal form of infectious peritonitis.","PeriodicalId":8625,"journal":{"name":"Athletic Therapy Today","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Control of chronic coronavirus infection in cats with the use of Phosprenyl and Gamavit\",\"authors\":\"S. Savoyskaya, I. Ogorodnikova, T. Kozhevnikova\",\"doi\":\"10.30917/ATT-VK-1814-9588-2021-3-13\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Feline enteropathogenic coronavirus affects the intestinal epithelium and causes inflammation of the intestinal mucosa in cats. In adult cats, the infection is usually asymptomatic, but the constant circulation of the coronavirus in the feline population can increase the likelihood of mutation leading to appearance of the virulent strain of the virus that cause feline infectious peritonitis - a deadly disease that develops in 5-10% of cats carrying the coronavirus. The aim of this work was to study the effect of the drugs Phosprenyl and Gamavit on the course of coronavirus infection in cats. A total of 29 cats were monitored. The diagnosis was confirmed by the detection of antibodies by the IHA method, as well as by ultrasound examination of the abdominal organs. Prescribed treatment: Phosprenyl per os, 1 ml , twice a day, course 2-4 months; Gamavit 1 time a day, s/c, course 10 days, with a repeated course after 3 weeks; 3-4 times. As symptomatic therapy, drugs were used to improve the condition of the stool. At the end of treatment, symptoms of gastrointestinal tract damage disappeared in all patients. If before the start of treatment, most patients showed signs of anemia (a decrease in the number of red blood cells and hemoglobin levels), leukocytosis with a predominance of segmented neutrophils, characteristic of infectious and inflammatory processes, and increased ESR, then at the end of therapy, these indicators were completely normalized. Thus, long-term therapy with the use of Phosprenyl and Gamavit helps to control the course of coronavirus infection in cats, prevent its exacerbation and transition to a highly lethal form of infectious peritonitis.\",\"PeriodicalId\":8625,\"journal\":{\"name\":\"Athletic Therapy Today\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2021-06-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Athletic Therapy Today\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.30917/ATT-VK-1814-9588-2021-3-13\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Athletic Therapy Today","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.30917/ATT-VK-1814-9588-2021-3-13","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

猫肠道致病性冠状病毒影响猫的肠上皮,并引起猫肠粘膜炎症。在成年猫中,感染通常是无症状的,但冠状病毒在猫群中的持续循环会增加突变的可能性,从而导致致命的病毒株出现,从而导致猫传染性腹膜炎,这种致命的疾病会在5-10%携带冠状病毒的猫身上发生。本工作的目的是研究药物Phospreny和Gamavit对猫冠状病毒感染过程的影响。共监测了29只猫。通过IHA法检测抗体以及腹部器官的超声检查证实了诊断。处方治疗:Phosprenyl每次口服,1毫升,每天两次,疗程2-4个月;Gamavit每天1次,s/c,疗程10天,3周后重复疗程;3-4次。作为症状治疗,药物被用来改善大便的状况。治疗结束时,所有患者的胃肠道损伤症状均消失。如果在治疗开始前,大多数患者表现出贫血(红细胞数量和血红蛋白水平下降)、白细胞增多(以分段中性粒细胞为主)、感染和炎症过程特征以及ESR增加的迹象,那么在治疗结束时,这些指标完全正常化。因此,使用Phospreny和Gamavit的长期治疗有助于控制猫的冠状病毒感染过程,防止其恶化并转变为高度致命的感染性腹膜炎。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Control of chronic coronavirus infection in cats with the use of Phosprenyl and Gamavit
Feline enteropathogenic coronavirus affects the intestinal epithelium and causes inflammation of the intestinal mucosa in cats. In adult cats, the infection is usually asymptomatic, but the constant circulation of the coronavirus in the feline population can increase the likelihood of mutation leading to appearance of the virulent strain of the virus that cause feline infectious peritonitis - a deadly disease that develops in 5-10% of cats carrying the coronavirus. The aim of this work was to study the effect of the drugs Phosprenyl and Gamavit on the course of coronavirus infection in cats. A total of 29 cats were monitored. The diagnosis was confirmed by the detection of antibodies by the IHA method, as well as by ultrasound examination of the abdominal organs. Prescribed treatment: Phosprenyl per os, 1 ml , twice a day, course 2-4 months; Gamavit 1 time a day, s/c, course 10 days, with a repeated course after 3 weeks; 3-4 times. As symptomatic therapy, drugs were used to improve the condition of the stool. At the end of treatment, symptoms of gastrointestinal tract damage disappeared in all patients. If before the start of treatment, most patients showed signs of anemia (a decrease in the number of red blood cells and hemoglobin levels), leukocytosis with a predominance of segmented neutrophils, characteristic of infectious and inflammatory processes, and increased ESR, then at the end of therapy, these indicators were completely normalized. Thus, long-term therapy with the use of Phosprenyl and Gamavit helps to control the course of coronavirus infection in cats, prevent its exacerbation and transition to a highly lethal form of infectious peritonitis.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Athletic Therapy Today
Athletic Therapy Today 医学-康复医学
自引率
0.00%
发文量
0
审稿时长
>12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信