有机磷阻燃剂的毒性

IF 1.9 4区 工程技术 Q2 ENGINEERING, MULTIDISCIPLINARY
B. Howell
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引用次数: 0

摘要

随着有机磷阻燃剂的开发和使用越来越普遍,人们对其潜在毒性的担忧也越来越多。迄今为止,大多数关于潜在毒性的研究都集中在简单的磷酸酯上,通常包括烷基酯和芳基酯,或者在某些情况下,甚至包括卤化磷酸酯(更应该将其列入有机卤素阻燃剂中)。将几种酯类纳入一项研究导致结论混乱。每一类磷酸酯应分别进行毒性评估。此外,对更有效的有机磷阻燃剂(对磷的氧化水平较低:膦酸盐、膦酸盐、磷氧化物)的潜在毒性研究甚少。现有的少数结果表明,这些化合物没有毒性或毒性很小(低于磷酸盐)。这一领域应该成为仔细详细研究的重点,以确定任何潜在的毒性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Toxicity of organophosphorus flame retardants
As the development and use of organophosphorus flame retardants have become more prevalent, concerns about potential toxicity are being raised. To date, most studies on potential toxicity have focused on simple phosphate esters and often include both alkyl and aryl esters or, in some cases, even halogenated phosphate esters (which should more properly be included among organohalogen flame retardants). The inclusion of several kinds of esters into a single study leads to muddled conclusions. Each class of phosphate esters should be subjected to toxicity assessment separately. Furthermore, the potential toxicity of the more effective (lower level of oxygenation at phosphorus: phosphonates, phosphinates, phosphine oxides) organophosphorus flame retardants has been little explored. The few results available suggest that these compounds exhibit no or minimal toxicity (lower than that of phosphates?). This represents an area that should be the focus of careful detailed studies to establish any potential toxicity.
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来源期刊
Journal of Fire Sciences
Journal of Fire Sciences 工程技术-材料科学:综合
CiteScore
4.00
自引率
0.00%
发文量
14
审稿时长
2.5 months
期刊介绍: The Journal of Fire Sciences is a leading journal for the reporting of significant fundamental and applied research that brings understanding of fire chemistry and fire physics to fire safety. Its content is aimed toward the prevention and mitigation of the adverse effects of fires involving combustible materials, as well as development of new tools to better address fire safety needs. The Journal of Fire Sciences covers experimental or theoretical studies of fire initiation and growth, flame retardant chemistry, fire physics relative to material behavior, fire containment, fire threat to people and the environment and fire safety engineering. This journal is a member of the Committee on Publication Ethics (COPE).
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