胸部和腹部的Eumisetoma:罕见的病例

Jimy Fran, Istiana Fiatiningsih, Ilhami Romus
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引用次数: 0

摘要

Mycetoma是一种由细菌(放线菌瘤)或真菌(真菌瘤)引起的皮肤、皮下、筋膜和骨骼的慢性肉芽肿性传染病,年龄在20-40岁的成年人中,男女比例分别为3,7:1。临床发现为无痛、实性和冷性皮下淋巴结。据报道,一名43岁的女性在过去一年中胸部、胃部、腋下和腿部出现无痛化脓性肿块。肿块为增生性瘢痕、萎缩性瘢痕、结节和红斑丘疹,伴有脓疱和鼻窦,分泌物呈绿黄色。该患者有在油棕农场工作的历史。苏木精-伊红的组织病理学检查显示化脓性肉芽肿性炎症,包括上皮样组织细胞、实体淋巴细胞和中性粒细胞,以及datia细胞。PAS(Periodic acid Schiff)染色显示阳性结果。根据体格检查和组织病理学检查,确诊为深部真菌病。真菌瘤是一种罕见的深部真菌病。需要支持性研究,如直接显微镜检查、活检组织病理学和培养来确定诊断。治疗方法包括抗真菌药物和手术。如果感染发生在胸腔或头部,则可能导致死亡。关键词:深部真菌病,真菌瘤,颗粒,霉菌瘤,鼻窦
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Eumisetoma pada Toraks dan Abdomen: Suatu Kasus Jarang
Mycetoma is a chronic granulomatous infectious disease of the skin, subcutis, fascia and bones caused by bacteria (actinomycetoma) or fungi (eumycetoma) in adults aged 20-40 years old, male to female ratio is 3,7:1 respectively. The clinical finding is a painless, solid and cold subcutaneous node. It has been reported a 43-year-old woman with a painless suppurative lump in her chest, stomach, armpits and legs in the past year. The lump were hypertrophic scars, atrophic scars, nodules and erythematous papules with pustules and sinuses, which excretes exudate greenish-yellow. The patient had a history of working in an oil palm farm. Histopathological examination of hematoxylin-eosin showed suppurative granulomatous inflammation consisting of epitheloid histiocytes, solid lymphocytes and neutrophils, and datia cells. PAS (Periodic acid-Schiff) staining showed positive results. The diagnosis of deep mycosis eumycetoma was confirmed based on physical examination and histopathological examination. Eumycetoma is a rare deep fungal disease. Supporting investigations such as direct microscopy, histopathology with biopsy, and culture are needed to establish the diagnosis. The therapies are antifungal drugs and surgery. Death is possible if the infection occurs in the chest or head cavity.Keywords: deep mycosis, eumycetoma, granules, mycetoma, sinuses
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