脊柱调整后心率变异性的改善:单次办公室访视的统计方法案例研究

J. Hart, Greenville South Carolina Hart Chiropractic
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引用次数: 3

摘要

引言:统计分析通常应用于集团层面。本研究分析了单次办公室访问期间的数据,作为一种新的方法,向临床医生和患者提供关于干预效果的实时反馈。在这项研究中,对脊椎按摩调整前后的心率变异性(HRV)进行了分析。方法:患者为一名成年女性,签署了研究同意书。在脊椎按摩调整前测量两次HRV,之后使用基于应用程序的技术测量一次。然后使用Grubbs检验,使用异常值在线计算器对三个HRV值(两个前值和一个后值)进行统计分析。结果:两个调整前HRV(rMSSD)读数始终较低:前1=16.0毫秒[ms]和前2=16.2毫秒。低HRV表明患者的神经系统功能不佳。患者的寰椎(C1)被触诊为轻微错位。这两个发现(低HRV和脊椎错位)表明存在脊椎按摩半脱位(寰椎)。对半脱位进行了调整,几分钟内HRV增加(改善)至27.5 ms。经计算,这种改善是一个具有统计学意义的异常值(p<0.05)。结论:本研究是一个例子,说明了如何将统计方法应用于一名患者在一次办公室访视期间的水平,以评估脊椎按摩调整的神经有效性。由于这是一个案例研究,结果可能不适用于所有患者。因此,对其他患者进行进一步研究,并延长随访时间,是合理的下一步行动。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Improvement in Heart Rate Variability Following Spinal Adjustment: A Case Study in Statistical Methodology for a Single Office Visit
Introduction: Statistical analysis is typically applied at the group level. The present study analyzes data during a single office visit as a novel approach providing real-time feedback to the clinician and patient regarding efficacy of an intervention. In this study, heart rate variability (HRV) was analyzed before versus after a chiropractic spinal adjustment. Methods: The patient is an adult female who signed a consent form for the study. HRV was measured twice before a chiropractic adjustment and once afterwards using app-based technology. The three HRV values (two pre and one post) were then statistically analyzed using an online calculator for outliers using Grubbs test. Results: The two pre-adjustment HRV (rMSSD) readings were consistently low: pre 1 = 16.0 milliseconds [ms] and pre 2 = 16.2 ms. The low HRV was an indicator that the patient’s nervous system was not functioning optimally. The patient’s atlas (C1) vertebra was palpated to be slightly out of alignment. These two findings (low HRV and vertebral misalignment) indicated the presence of a chiropractic subluxation (of the atlas vertebra). The subluxation was adjusted and within minutes the HRV increased (improved) to 27.5 ms. This improvement was calculated to be a statistically significant outlier (p < 0.05). Conclusion: This study is an example of how statistical methods can be applied to the level of an individual patient during one office visit to assess neurological effectiveness of a chiropractic adjustment. Since this is a case study, the results may not apply to all patients. Therefore, further studies in other patients, and for longer follow-up times, are reasonable next steps.
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