一种新的液刀免疫治疗癌症的折衷方法:UMIPIC,它可能会超过所有阶段实体瘤的许多手术、化疗和放射治疗

Baofa Yu
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引用次数: 0

摘要

近年来,癌症免疫治疗越来越流行,许多新药如PD1和PDl-1已被FDA批准,但在癌症治疗的临床实践中,它对晚期癌症的疗效非常有限,因此医生开始将综合方案与PD1联合化疗作为一种新的策略,具有更好的临床效益。由于化疗和放射治疗总是会产生脱发、呕吐和中性粒细胞减少等副作用,而且许多癌症后期手术受限,而且手术也会损害体型和功能,癌症被切除并重建,将胃放入胸部,胃从未有过正常功能;很多病例表明,由于肿瘤位于特殊部位,如阴道后壁或阴道性交部位,手术是不允许进行的,如果切除这些部位的肿瘤,就会形成一个连接直肠的洞。由于毒性极强的副作用,许多癌症患者无法成功完成一次手术或一个完整的化疗或放射治疗过程,有些病例甚至因患者耐受性差而死于手术或化疗或放射疗法的副作用。抗癌药物的极端副作用通常是由于此类药物对患者体内肿瘤的靶点特异性较差而引起的。药物在患者的大多数正常器官以及预期的靶肿瘤中循环(只有不到5%的药物到达肿瘤),而超过95%的药物在患者全身循环。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Novel Eclectic Approach for Cancer Therapy with Liquid Knife & Immuno Therapy: UMIPIC, it may Overtake many Surgery, Chemotherapy and Radiation Therapy for all Stages of Solid Tumor
Recent years cancer immunological therapy is getting very popular and many new drug have been approved by FDA like PD1 and PDl-1, however, in clinical practice of cancer treatment, it looks very limited efficacy for advanced cancer, so that physician started to use comprehensive plan by combination chemotherapy with PD1 as a novel strategy with a better clinical benefit. Since chemotherapy and radiation therapy always produce the side effect like loss hair, vomit and neutropenia, and surgery is limited for many later stages of cancers, also surgery damages body shapes with functions, esophageal cancer was removed with reconstruction and put stomach into chest and stomach never has normal function; a lot of cases showed surgery can’t be performed because tumor location in special site, like tumor location in posterior vaginal wall or vaginal carnal, surgery just is not allowed to do the procedure, if remove the tumor in these location, it will make a hole to connect to the rectal. Because of the extremely toxic side effects, many cancer patients cannot be successfully completed a surgery or a complete course of chemotherapy or radiation therapy, and some cases even die from the side effects of surgery or chemotherapy or radiation therapy due to a patient’s poor tolerance. The extreme side effects of anti-cancer drugs are often caused by the poor target specificity of such drugs regarding the tumor in the patient’s body. The drugs circulate through most normal organs of patients as well as the intended target tumors (less than 5% of the drug reach the tumor), while over 95% of the drug circulates through the whole body of the patient.
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