循环性死亡后捐献胰腺移植

Q4 Medicine

Transplantation Reports Pub Date : 2022-12-01 DOI:10.1016/j.tpr.2022.100120

Jeffery Campsen, Michael A. Zimmerman

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引用次数: 1

摘要

糖尿病是世界范围内发病率和死亡率的主要原因。胰腺移植已经发展成为一个可行的治疗选择，在这一患者群体。虽然大多数手术是同时胰肾(SPK)或胰肾后胰肾(PAK)进行的，但由此产生的血糖控制可显著延缓心血管疾病的进展。目前，器官严重短缺。循环性死亡后捐赠可能是增加胰腺供体池的一种策略。在此，我们研究了影响器官选择的临床参数，并回顾了目前在DCD捐赠情况下胰腺移植的经验。

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Pancreas transplantation following donation after circulatory death

Diabetes mellitus is a major cause of morbidity and mortality worldwide. Pancreas transplantation has evolved into a viable treatment option in this patient population. While the majority of procedures are performed as either simultaneous pancreas-kidney (SPK) or pancreas after kidney (PAK), the resulting glycemic control leads to a significant delay in the progression of cardiovascular disease. At present, there is a critical organ shortage. Donation after circulatory death (DCD) may be a strategy to increase the pancreas donor pool. Herein, we examine the clinical parameters that impact organ selection and review the current experience with pancreas transplantation in the setting of DCD donation.

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来源期刊

Transplantation Reports Medicine-Transplantation

CiteScore

0.60

自引率

0.00%

发文量

审稿时长

101 days

期刊介绍： To provide to national and regional audiences experiences unique to them or confirming of broader concepts originating in large controlled trials. All aspects of organ, tissue and cell transplantation clinically and experimentally. Transplantation Reports will provide in-depth representation of emerging preclinical, impactful and clinical experiences. -Original basic or clinical science articles that represent initial limited experiences as preliminary reports. -Clinical trials of therapies previously well documented in large trials but now tested in limited, special, ethnic or clinically unique patient populations. -Case studies that confirm prior reports but have occurred in patients displaying unique clinical characteristics such as ethnicities or rarely associated co-morbidities. Transplantation Reports offers these benefits: -Fast and fair peer review -Rapid, article-based publication -Unrivalled visibility and exposure for your research -Immediate, free and permanent access to your paper on Science Direct -Immediately citable using the article DOI