组织工程气管血管化的研究进展

Zhihao Wang, Boyou Zhang, Jun Ma
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引用次数: 0

摘要

组织工程是一门综合材料科学、生命科学和工程学的综合性学科,通过细胞或组织重建来修复、改善和保存受损的组织或器官。近年来,随着组织工程技术的快速发展,组织工程气管逐渐成为气管替代治疗的新途径。然而,由于供应气管的血管细长且周期性分布,气管移植物无法获得足够的血液供应来维持其需求,其血管化问题成为组织工程气管发展的主要障碍之一。在组织工程气管的构建中,种子细胞、气管支架和生长因子的血管化策略逐渐成为研究的热点。本文对组织工程气管血管化的研究现状进行了综述。关键词:组织工程;血管化;气管支架;种子细胞;生长因子
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Research progress in tissue-engineered tracheal vascularization
Tissue engineering is a comprehensive discipline that combines materials science, life sciences, and engineering to repair, and improve and preserve damaged tissues or organs through cell or tissue reconstruction. In recent years, with the rapid development of tissue engineering technology, tissue engineering trachea has gradually become a new approach to tracheal replacement therapy. However, due to the slender and periodic distribution of the blood vessels supplying the trachea, tracheal grafts cannot obtain sufficient blood supply to maintain its demand, making its vascularization problem one of the major obstacles to the development of tissue engineering trachea. In the construction of tissue engineering trachea, the vascularization strategy of seed cells, tracheal scaffold and growth factors have gradually become the focus of research. In this paper, the current researches on tissue engineering tracheal vascularization were reviewed. Key words: Tissue engineering; Vascularization; Tracheal scaffold; Seed cells; Growth factors
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