大学生多囊卵巢综合征患病率的评估:加尔各答的一项病例对照研究

M. Chatterjee, S. Bandyopadhyay
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引用次数: 8

摘要

背景:多囊卵巢综合征(PCOS)是育龄妇女最常见的内分泌疾病之一。近来,由于环境变化和生活方式紊乱,该病呈上升趋势,影响到全球4%至26%的青少年和年轻妇女。最初,这种情况在年轻女孩中无症状,在青春期后期发展为月经不规则、肥胖、高雄激素症,最终在中年左右发展为胰岛素抵抗、高血压、2型糖尿病、心血管疾病和不孕症。目的:早期诊断是早期干预的必要条件,包括改变生活方式以预防多囊卵巢综合征的直接和慢性后果。材料与方法:我们的研究设计是一项基于横断面问卷的调查,于2017年9月至2018年3月进行,旨在调查多囊卵巢综合征的患病率及其与身体成分变量的关系。研究人群包括随机选择的所有学科的学生(18-20岁年龄组)。根据鹿特丹标准,使用结构化问卷从学生中收集数据,并使用标准技术进行人体测量。结果:约28%的大学生处于多囊卵巢综合征的高危人群。超过85%的PCOS患者有少经,19%有多毛,41%有痤疮,63%有情绪障碍,22%有阳性家族史。此外,多囊卵巢综合征学生的身体质量指数比同年龄组的正常女性表现出一级肥胖的趋势。结论:本研究旨在提高学生对PCOS早期准确诊断的认识,这是治疗PCOS的第一步。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Assessment of the prevalence of polycystic ovary syndrome among the college students: A case–control study from Kolkata
Background: Polycystic ovary syndrome (PCOS) is one of the most common endocrine disorders in women of reproductive age. Of late, the disease is on its rise due to environmental changes as well as lifestyle disorders, affecting 4%–26% of adolescent and young women all over the globe. Initially, this condition is asymptomatic in young girls, progressing toward menstrual irregularities, obesity, hyperandrogenism in late puberty and eventually developing insulin resistance, hypertension, type 2 diabetes, cardiovascular diseases, and infertility around middle age. Aims: Early diagnosis is necessary for early intervention, including lifestyle modifications to prevent the immediate and chronic consequences of PCOS. Materials and Methods: Our study design was of a cross-sectional questionnaire-based survey, conducted from September 2017 to March 2018 to investigate the prevalence of PCOS and its association with body composition variables. The study population comprised randomly chosen students (age group 18–20 years) of all discipline. The data were collected from the students using structured questionnaire with Rotterdam's criteria, and anthropometric measurements were taken using standard techniques. Results: Approximately 28% of the college students were found to be at high risk of developing PCOS. More than 85% of the PCOS cases had oligomenorrhea, 19% were hirsute, 41% had acne, 63% had emotional disturbance, and 22% with a positive family history. Furthermore, the body mass index of the PCOS students demonstrated a trend of Grade 1 obesity than the normal females of the same age group. Conclusion: The present study is an attempt to create increased awareness among the students for early and accurate diagnosis, which is the primary step in managing PCOS.
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