乳房缩小术后预防性抗生素应用的单中心回顾性队列研究

IF 0.7 4区 医学 Q4 SURGERY
Plastic surgery Pub Date : 2024-05-01 Epub Date: 2022-06-15 DOI:10.1177/22925503221107220
Véronique M Doucet, Jakob J Weirathmueller, Graham J McLeod, Kenneth A Murray
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引用次数: 0

摘要

简介:乳房缩小乳房成形术(BRM)是整形外科医生治疗乳房肥大患者的常见手术。尽管缺乏证据表明其在预防手术部位感染(SSIs)方面的有效性,但通常在术前预防性静脉注射BRM抗生素,然后在术后几天预防性口服抗生素。本研究的目的是确定在BRM中,与单剂量术前预防性抗生素相比,添加预防性术后抗生素是否更有效地预防SSI。方法:对一位资深整形外科医生的124例择期BRM病例进行回顾性分析。根据手术地点组成两个研究组,每组被分配不同的抗生素方案。第一种抗生素方案包括术前单次静脉注射抗生素(第1组),而第二种方案包括术后静脉注射抗生素,然后口服抗生素5天(第2组)。结果:总的SSI发生率为5.6%。第1组的感染率为8.1%,而第2组为3.2%(P值.44)。总的来说,并发症的发生率为29.0%;第1组为38.7%,第2组为19.4%(P值.03)。并发症包括35例伤口愈合延迟,7例SSI和2例需要清除的血肿。结论:研究结果表明,BRM术后预防性抗生素的使用对SSIs的发生率没有显著影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Postoperative Prophylactic Antibiotic Use in Breast Reduction Mammoplasty: A Single Centre Retrospective Cohort Study.

Introduction: Breast reduction mammoplasty (BRM) is a common procedure performed by plastic surgeons treating patients with hypermastia. It is customary to give preoperative prophylactic intravenous antibiotics for BRM, followed by several days of postoperative prophylactic oral antibiotics, despite the lack of evidence of their effectiveness in preventing surgical site infections (SSIs). The purpose of this study is to determine if the addition of prophylactic postoperative antibiotics is more effective in preventing SSIs in comparison to a single dose of preoperative prophylactic antibiotics in BRM. Methods: A retrospective analysis of 124 elective BRM cases by a single senior plastic surgeon was completed. Two study groups were formed based on the location of surgery and each group was assigned a different antibiotic regimen. The first antibiotic regimen consisted of a single preoperative intravenous dose of antibiotics (group 1), while the second regimen consisted of a preoperative intravenous dose followed by a 5-day course of oral antibiotics (group 2). Results: Overall SSI rate was 5.6%. Infection rate in group 1 was 8.1% in comparison to 3.2% for group 2 (P value .44). Overall, the incidence of complications was 29.0%; 38.7% in group 1 and 19.4% in group 2 (P value .03). Complications consisted of 35 cases of delayed wound healing, 7 SSIs and 2 hematomas requiring evacuation. Conclusion: Study results demonstrated that the use of postoperative prophylactic antibiotics for BRM had no significant effect on the rate of SSIs.

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来源期刊
Plastic surgery
Plastic surgery Medicine-Surgery
CiteScore
1.70
自引率
0.00%
发文量
73
期刊介绍: Plastic Surgery (Chirurgie Plastique) is the official journal of the Canadian Society of Plastic Surgeons, the Canadian Society for Aesthetic Plastic Surgery, Group for the Advancement of Microsurgery, and the Canadian Society for Surgery of the Hand. It serves as a major venue for Canadian research, society guidelines, and continuing medical education.
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