{"title":"PMQR决定因子在乌克兰哈尔科夫市Pyeloephritis住院患者临床分离的革兰氏阴性尿路病原体中的表达","authors":"O. Chub, A. Bilchenko, I. Teslenko","doi":"10.2174/1874303X01710010001","DOIUrl":null,"url":null,"abstract":"Resistance to beta-lactams and fluoroquinolones has been increasing in the treatment of urinary tract infections (UTIs), worldwide. Recent studies in Europe and the United States have demonstrated that steady increase in the rate of uropathogen’s resistance to commonly prescribed antibiotics is associated with plasmid-mediated resistance genes existence. According to the published data, acquirеd rеsistance to quinolones is predоminantly mediated by plasmid-mediated quinolone resistance determinants (PMQR) that cоmpromise the efficаcу of the first, second and third generation quinolones.","PeriodicalId":38952,"journal":{"name":"Open Urology and Nephrology Journal","volume":"10 1","pages":"1-10"},"PeriodicalIF":0.0000,"publicationDate":"2017-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"PMQR Determinants Expression in Gram-negative Uropathogens Clinically Isolated from Hospitalized Patients with Pyelonephritis in Kharkiv, Ukraine\",\"authors\":\"O. Chub, A. Bilchenko, I. Teslenko\",\"doi\":\"10.2174/1874303X01710010001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Resistance to beta-lactams and fluoroquinolones has been increasing in the treatment of urinary tract infections (UTIs), worldwide. Recent studies in Europe and the United States have demonstrated that steady increase in the rate of uropathogen’s resistance to commonly prescribed antibiotics is associated with plasmid-mediated resistance genes existence. According to the published data, acquirеd rеsistance to quinolones is predоminantly mediated by plasmid-mediated quinolone resistance determinants (PMQR) that cоmpromise the efficаcу of the first, second and third generation quinolones.\",\"PeriodicalId\":38952,\"journal\":{\"name\":\"Open Urology and Nephrology Journal\",\"volume\":\"10 1\",\"pages\":\"1-10\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-03-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Open Urology and Nephrology Journal\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/1874303X01710010001\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Open Urology and Nephrology Journal","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/1874303X01710010001","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
PMQR Determinants Expression in Gram-negative Uropathogens Clinically Isolated from Hospitalized Patients with Pyelonephritis in Kharkiv, Ukraine
Resistance to beta-lactams and fluoroquinolones has been increasing in the treatment of urinary tract infections (UTIs), worldwide. Recent studies in Europe and the United States have demonstrated that steady increase in the rate of uropathogen’s resistance to commonly prescribed antibiotics is associated with plasmid-mediated resistance genes existence. According to the published data, acquirеd rеsistance to quinolones is predоminantly mediated by plasmid-mediated quinolone resistance determinants (PMQR) that cоmpromise the efficаcу of the first, second and third generation quinolones.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
