三氟乙酸应用十年新进展

IF 1.9 4区化学 Q2 CHEMISTRY, ORGANIC

Mini-reviews in Organic Chemistry Pub Date : 2023-05-11 DOI:10.2174/1570193x20666230511121812

Dr. Ravi Varala, M. Alam, Vittal Seema

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引用次数: 0

摘要

自20世纪初发现以来，三氟乙酸（通常称为TFA）在有机合成中作为溶剂和催化剂/试剂得到了广泛应用。TFA可用于促进多种化学转化，包括重排、官能团脱保护、缩合、加氢芳基化和三氟烷基化等。这篇十年一次的小型综述考察了从2013年年中到现在TFA的关键合成应用，为有机化学研究界提供了一个机会，深入研究这种强酸、水溶性和低沸点试剂的众多不同应用。

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A Decennial Update on the Applications of Trifluroacetic acid

Since its discovery at the beginning of the 20th century, trifluoroacetic acid, commonly known as TFA, has seen extensive application in organic synthesis both as a solvent and as a catalyst/reagent. TFA can be used to facilitate a wide variety of chemical transformations, including rearrangements, functional group deprotections, condensations, hydroarylations and trifluoroalkylations, among others. The decennial mini-review examines key TFA synthetic applications from the middle of 2013 to the present, providing the organic chemistry research community with an opportunity to delve deeply into the numerous and varied applications of this strong acid, water-miscible, and low boiling point reagent.

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来源期刊

Mini-reviews in Organic Chemistry 化学-有机化学

CiteScore

4.50

自引率

4.30%

发文量

116

审稿时长

>12 weeks

期刊介绍： Mini-Reviews in Organic Chemistry is a peer reviewed journal which publishes original reviews on all areas of organic chemistry including organic synthesis, bioorganic and medicinal chemistry, natural product chemistry, molecular recognition, and physical organic chemistry. The emphasis will be on publishing quality papers very rapidly, without any charges. The journal encourages submission of reviews on emerging fields of organic chemistry including: Bioorganic Chemistry Carbohydrate Chemistry Chemical Biology Chemical Process Research Computational Organic Chemistry Development of Synthetic Methodologies Functional Organic Materials Heterocyclic Chemistry Macromolecular Chemistry Natural Products Isolation And Synthesis New Synthetic Methodology Organic Reactions Organocatalysis Organometallic Chemistry Theoretical Organic Chemistry Polymer Chemistry Stereochemistry Structural Investigations Supramolecular Chemistry