表面活性剂蛋白d水平与肥胖和2型糖尿病的关系

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL

Gomal Journal of Medical Sciences Pub Date : 2020-12-08 DOI:10.46903/gjms/18.01.2080

H. Alkwai, Shimaa Mohammad Aboelnaga, R. Hussain, F. Khatoon

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引用次数: 1

摘要

表面活性蛋白D (SP-D)是肺先天免疫的重要组成部分。它主要由2型肺泡和支气管上皮细胞产生，但也存在于肺外组织和血液中。它作为主要的宿主防御吸入的微生物。它还通过激活T细胞来增强适应性免疫。SP-D缺乏可导致上呼吸道和下呼吸道感染。肥胖在成人和儿童中已达到全球流行病的程度，并与许多合并症和胰岛素抵抗有关。2型糖尿病和肥胖与复发性肺部和肺外感染高度相关。本研究的主要目的是确定血清表面活性蛋白D水平与肥胖和2型糖尿病的关系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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SURFACTANT PROTEIN D LEVELS WITH OBESITY AND TYPE 2 DIABETES MELLITUS

Surfactant protein D (SP-D) is an important component of pulmonary innate immunity. It is mainly produced by type 2 alveolar and bronchial epithelial cells, but is also found in extra pulmonary tissues and blood. It acts as a primary host defense against inhaled microorganisms. It also enhances adaptive immunity by activating T cells. SP-D deficiency can lead to upper and lower respiratory tract infections. Obesity has reached global epidemic proportions in both adults and children and is associated with numerous co-morbidities and insulin resistance. Type 2 diabetes & obesity are highly associated with recurrent pulmonary & extra pulmonary infections. The primary objective of this study was to determine the association of serum surfactant protein D levels with obesity and type 2 diabetes mellitus.

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来源期刊

Gomal Journal of Medical Sciences MEDICINE, GENERAL & INTERNAL-

CiteScore

0.60

自引率

80.00%

发文量

审稿时长

40 weeks