高频重复经颅磁刺激左背外侧前额叶皮质治疗精神分裂症患者阴性症状后新发强迫症

IF 2.4 4区医学 Q3 NEUROSCIENCES

Clinical Psychopharmacology and Neuroscience Pub Date : 2019-08-01 DOI:10.9758/cpn.2019.17.3.443

H. Garg, Saurabh Kumar, Swarndeep Singh, Nand Kumar, R. Verma

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引用次数: 5

摘要

强迫症和/或强迫症（OCD）经常与精神分裂症合并，尽管它们之间的确切临床和病因关系尚不清楚。在这里，我们描述了一个病例，据我们所知，这是一名患者首次报告新发强迫症，该患者在左后外侧额前皮质接受高频重复经颅磁刺激，作为精神分裂症阴性症状的辅助治疗。本报告支持了我们对强迫症的理解，强迫症是一种大脑疾病，涉及额前皮层的过度活动和皮质-纹状体丘脑皮层回路功能障碍。

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New Onset Obsessive Compulsive Disorder Following High Frequency Repetitive Transcranial Magnetic Stimulation over Left Dorsolateral Prefrontal Cortex for Treatment of Negative Symptoms in a Patient with Schizophrenia

Obsessive-compulsive symptoms and/or obsessive-compulsive disorders (OCD) are frequently comorbid with schizophrenia, though the exact clinical and etiological relationship between them is poorly understood. Here we describe a case that, to the best of our knowledge, is the first report of new-onset OCD in a patient who was receiving high-frequency repetitive transcranial magnetic stimulation over left dorsolateral pre-frontal cortex as an adjuvant therapy for negative symptoms of schizophrenia. Thisreport supports our understanding of OCD as a brain disorder involving hyper-activity of pre-frontal cortex and cortico-striatal-thalamo-cortical circuit dysfunction.

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来源期刊

Clinical Psychopharmacology and Neuroscience NEUROSCIENCESPHARMACOLOGY & PHARMACY-PHARMACOLOGY & PHARMACY

CiteScore

4.70

自引率

12.50%

发文量

期刊介绍： Clinical Psychopharmacology and Neuroscience (Clin Psychopharmacol Neurosci) launched in 2003, is the official journal of The Korean College of Neuropsychopharmacology (KCNP), and the associate journal for Asian College of Neuropsychopharmacology (AsCNP). This journal aims to publish evidence-based, scientifically written articles related to clinical and preclinical studies in the field of psychopharmacology and neuroscience. This journal intends to foster and encourage communications between psychiatrist, neuroscientist and all related experts in Asia as well as worldwide. It is published four times a year at the last day of February, May, August, and November.