{"title":"单胺类和犬尿氨酸参与注意缺陷多动障碍或多动综合征的发病机制","authors":"M. Uzbekov","doi":"10.19080/GJIDD.2018.05.555667","DOIUrl":null,"url":null,"abstract":"The aetiology of ADHD/HKS is not known and pathogenesis is not clear. It has been shown that changes in the central monoaminergic systems play important role in ADHD/HKS [3,4]. Campbell M and Spenser E.K [5] wrote that “It remains to be shown where discrete biochemically based subgroups show a different response to drugs: to psychostimulants, imipramine or neuroleptics” (p. 273). In spite that it was written 30 years ago the problem still remains urgent.","PeriodicalId":93559,"journal":{"name":"Global journal of intellectual & developmental disabilities","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2018-12-19","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Monoamines and Kynurenine Involvement in Pathogenetic Mechanisms of Attention Deficit Hyperactivity Disorder or Hyperkinetic Syndrome\",\"authors\":\"M. Uzbekov\",\"doi\":\"10.19080/GJIDD.2018.05.555667\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The aetiology of ADHD/HKS is not known and pathogenesis is not clear. It has been shown that changes in the central monoaminergic systems play important role in ADHD/HKS [3,4]. Campbell M and Spenser E.K [5] wrote that “It remains to be shown where discrete biochemically based subgroups show a different response to drugs: to psychostimulants, imipramine or neuroleptics” (p. 273). In spite that it was written 30 years ago the problem still remains urgent.\",\"PeriodicalId\":93559,\"journal\":{\"name\":\"Global journal of intellectual & developmental disabilities\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2018-12-19\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Global journal of intellectual & developmental disabilities\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.19080/GJIDD.2018.05.555667\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Global journal of intellectual & developmental disabilities","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.19080/GJIDD.2018.05.555667","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Monoamines and Kynurenine Involvement in Pathogenetic Mechanisms of Attention Deficit Hyperactivity Disorder or Hyperkinetic Syndrome
The aetiology of ADHD/HKS is not known and pathogenesis is not clear. It has been shown that changes in the central monoaminergic systems play important role in ADHD/HKS [3,4]. Campbell M and Spenser E.K [5] wrote that “It remains to be shown where discrete biochemically based subgroups show a different response to drugs: to psychostimulants, imipramine or neuroleptics” (p. 273). In spite that it was written 30 years ago the problem still remains urgent.