体重指数是肥胖青少年贫血的潜在生物标志物吗?

Shubhra Pande , Rajeev Ranjan , Valentina A. Kratasyuk
{"title":"体重指数是肥胖青少年贫血的潜在生物标志物吗?","authors":"Shubhra Pande ,&nbsp;Rajeev Ranjan ,&nbsp;Valentina A. Kratasyuk","doi":"10.1016/j.jnim.2018.11.001","DOIUrl":null,"url":null,"abstract":"<div><p>The two paradoxical major health problems namely obesity and anemia are confirmed to affect millions around the world. Hepcidin, a protein synthesized in liver is a negative iron binding regulator. There is an affirmative relation between hepcidin and leptin levels and an inverse co-relation between hepcidin and iron status due to inflammation mediated by obesity in adolescents. So this implicates an alliance between anemia and obesity wherein weight reduction can be a powerful medium to improve iron absorption in obese adolescents. Also the Body Mass Index can serve as a preliminary non-invasive screening tool to identify potential adolescents prone to anemia.</p></div>","PeriodicalId":91757,"journal":{"name":"Journal of nutrition & intermediary metabolism","volume":"15 ","pages":"Pages 1-2"},"PeriodicalIF":0.0000,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.jnim.2018.11.001","citationCount":"11","resultStr":"{\"title\":\"Is Body Mass Index a potential biomarker for anemia in obese adolescents?\",\"authors\":\"Shubhra Pande ,&nbsp;Rajeev Ranjan ,&nbsp;Valentina A. Kratasyuk\",\"doi\":\"10.1016/j.jnim.2018.11.001\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>The two paradoxical major health problems namely obesity and anemia are confirmed to affect millions around the world. Hepcidin, a protein synthesized in liver is a negative iron binding regulator. There is an affirmative relation between hepcidin and leptin levels and an inverse co-relation between hepcidin and iron status due to inflammation mediated by obesity in adolescents. So this implicates an alliance between anemia and obesity wherein weight reduction can be a powerful medium to improve iron absorption in obese adolescents. Also the Body Mass Index can serve as a preliminary non-invasive screening tool to identify potential adolescents prone to anemia.</p></div>\",\"PeriodicalId\":91757,\"journal\":{\"name\":\"Journal of nutrition & intermediary metabolism\",\"volume\":\"15 \",\"pages\":\"Pages 1-2\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.jnim.2018.11.001\",\"citationCount\":\"11\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of nutrition & intermediary metabolism\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2352385918300872\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of nutrition & intermediary metabolism","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2352385918300872","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 11

摘要

肥胖和贫血这两个矛盾的主要健康问题被证实影响着全世界数百万人。Hepcidin是一种在肝脏中合成的蛋白质,是一种负铁结合调节剂。hepcidin与瘦素水平呈正相关,hepcidin与青少年肥胖介导的炎症引起的铁状态呈负相关。因此,这暗示了贫血和肥胖之间的联系,减肥可以成为改善肥胖青少年铁吸收的有力手段。此外,身体质量指数可以作为一个初步的非侵入性筛查工具,以确定潜在的青少年易患贫血。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Is Body Mass Index a potential biomarker for anemia in obese adolescents?

The two paradoxical major health problems namely obesity and anemia are confirmed to affect millions around the world. Hepcidin, a protein synthesized in liver is a negative iron binding regulator. There is an affirmative relation between hepcidin and leptin levels and an inverse co-relation between hepcidin and iron status due to inflammation mediated by obesity in adolescents. So this implicates an alliance between anemia and obesity wherein weight reduction can be a powerful medium to improve iron absorption in obese adolescents. Also the Body Mass Index can serve as a preliminary non-invasive screening tool to identify potential adolescents prone to anemia.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
自引率
0.00%
发文量
0
审稿时长
12 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信