Bone healing efficacy of Lakshagrishtiksheeradi churna over Calcium +Vit D3 in Avrana Kanda Bhagna (Closed fractures of long bones) - A Randomized controlled clinical trial

Background: Delayed bone healing or non-union of fractures owns high rate of complications, morbidity and mortality. It possesses enormous burden to both patients and healthcare system. Till now there is no proven molecule which could enhance the process of bone healing. Hence, time tested Lakshagrishtiksheeradi churna, an Ayurvedic formulation is explored for its efficacy in the management of Avrana Kanda Bhagna. Objective: To Evaluate Bone healing efficacy of Lakshagrishtiksheeradi churna in Avrana Kanda Bhagna. Methods: Total 30 patients meeting the inclusion criteria of Avrana Kanda Bhagna, with age group 14-50 years participated in the study. They were randomly divided into two groups. Group A received Lakshagrishtiksheeradi churna 6 grams and group B Tab Calcium 500 mg +VitD3 respectively twice a day for 30days. Assessments were done through various variables like Pain, Tenderness, Swelling and Bone callus index. Follow up visit was on 30th day and 45th day. Results: Study showed that both Lakshagrishtiksheeradi churna and Calcium + Vit D3 produced improvement in most of the variables and were comparable. However, marked improvements were seen in various variables like Pain, Tenderness, Swelling and Bone callus Index. Conclusion: Clinical efficacy showed that Lakshagrishtiksheeradi churna is safe, effective oral medication in the management of Avrana Kanda Bhagna (Closed Fractures of long bones).