周期性痉挛性眼球运动异常:四例病例描述及机制假说

Haitian Nan, Y. Jing
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引用次数: 1

摘要

动眼肌轻瘫伴周期性痉挛(OPCS)是一种罕见的先天性疾病。它通常在出生时或出生后两年内出现。由于动脉瘤压迫神经和放射治疗后获得性OPCS已被报道。OPCS的特点是单侧第三神经麻痹,伴有周期性痉挛,引起眼睑抬高、缩小和收缩一块或多块由第三神经支配的眼外肌。在此,我们报告了4例患有这种罕见眼病的患者,并提出了可能的机制和鉴别诊断。在病例4中,伽玛刀放射手术继发的症状与眼神经肌强直(ONM)的症状令人困惑地相似。迄今为止,文献中尚未报道cop与伽玛刀放射手术的关联。cop似乎在ONM的外围机制上有一些相似之处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Oculomotor Paresis with Cyclic Spasms: Description of Four Cases and Hypothesis of the Mechanism
Oculomotor paresis with cyclic spasms (OPCS) is a rare and usually congenital disorder. It typically presents at birth or within the first 2 years of life. Acquired OPCS resulting from aneurysm compression on the nerve and after irradiation therapy has been reported. OPCS is characterized by unilateral third nerve paresis with periodic spasms causing eyelid elevation, miosis and contraction of 1 or more of the extraocular muscles innervated by the third nerve. Here we report four patients with this rare ocular condition, and propose possible mechanisms and differential diagnoses for their presentation. In case of patient #4 the symptoms secondary to gamma knife radiosurgery is confusingly similar to that of Ocular neuromyotonia (ONM). The association of COPS and gamma knife radiosurgery is hitherto unreported in the literature. It seems likely that COPS may share some similarity on peripheral mechanisms of ONM.
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