单侧视网膜分支静脉闭塞及正常眼桡骨乳头周围毛细血管密度的评价

IF 2.3 Q2 OPHTHALMOLOGY
C. U. Atılgan, Y. Goker, Gözde Hondur, P. Kosekahya, A. M. Koçer, M. Çıtırık
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引用次数: 2

摘要

背景:鉴于单侧视网膜分支静脉闭塞(BRVO)和青光眼具有共同的全身血管危险因素,BRVO患者的同侧眼可能增加青光眼的风险。目的:应用光学相干断层扫描血管造影(OCTA)分析单侧BRVO眼和正常眼的径向乳头周围毛细血管密度(RPCD)。设计:横断面、前瞻性研究。方法:选取80例患者120只眼,其中BRVO患眼40只,BRVO伴眼40只,对照眼40只。OCTA分析rcd、视网膜神经纤维层厚度(RNFLT)。结果:患眼的全像、乳头周围区、所有半球和象限的RPCDs均低于对照组和对照组,差异均有统计学意义(p < 0.05)。结论:与健康对照相比,单侧BRVO患者的眼侧RPCD值较低,但RNFLT值相似。这些结果可能表明BRVO和青光眼发展的共同血管机制和危险因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluation of the radial peripapillary capillary density in unilateral branch retinal vein occlusion and the unaffected fellow eyes
Background: Given that unilateral branch retinal vein occlusion (BRVO) and glaucoma share common systemic vascular risk factors, the fellow eyes of patients with BRVO may be at increased risk of glaucoma. Objectives: To analyze the radial peripapillary capillary density (RPCD) in eyes with unilateral BRVO and their unaffected fellow eyes using optical coherence tomography angiography (OCTA). Design: Cross-sectional, prospective study. Methods: The study included 120 eyes of 80 patients: 40 affected eyes of BRVO, 40 fellow eyes of BRVO, and 40 control eyes. The RPCD, retinal nerve fiber layer thickness (RNFLT) were analyzed using OCTA. Results: RPCDs in the whole image, peripapillary region, all the hemispheres, and quadrants were statistically lower in the affected eyes than in both the fellow and control eyes (p < 0.05 for all). RPCD values in the whole image and the peripapillary region were significantly lower in the fellow eyes than in the control eyes (p = 0.013, and p = 0.021, respectively). RNFLTs in the peripapillary region, inferior hemisphere and inferior quadrant were significantly lower in the affected eyes than in the control eyes (p < 0.05 for all). No significant differences were detected between the fellow eyes and the control eyes in term of RNFLT values in any regions (p > 0.05 for all). Conclusion: Lower RPCD values despite similar RNFLT values were observed in the fellow eyes of patients with unilateral BRVO compared with healthy controls. These results may indicate the shared vascular mechanisms and risk factors that account for the development of BRVO and glaucoma.
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来源期刊
CiteScore
4.50
自引率
0.00%
发文量
44
审稿时长
12 weeks
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