多普勒超声评价Zaria绝经前和绝经后宫颈癌症妇女及对照组子宫动脉血流模式

IF 0.1 Q4 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING
I. Zaria, I. Garba, Chom Dung, Ibinaiye Oluluke, Lawal Suleiman
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引用次数: 0

摘要

背景:癌症仍然是一个重要的健康问题,特别是在发展中国家,这些国家约占世界癌症宫颈癌负担的85%。发现多普勒超声在评估这些患者中的作用可以降低成本并改善管理。目的:本研究旨在评估尼日利亚一家教学医院绝经前和绝经后宫颈癌症患者的多普勒血流参数,并与正常对照组进行比较。方法:这是一项为期7个月(2016年8月至2017年2月)的前瞻性病例对照观察性研究,在尼日利亚扎里亚的艾哈迈杜·贝洛大学教学医院进行。81名癌症宫颈癌患者和81名年龄匹配的对照者对子宫主要动脉进行了经腹多普勒超声检查。使用美国伊利诺伊州芝加哥市的SPSS 20.0版对数据进行分析。两组之间的子宫动脉指数进行统计学差异,P<0.05被认为具有统计学意义。结果:患者的平均阻力指数(RI)和搏动指数(PI)分别为0.64±0.12和1.26±0.31,对照组分别为0.88±0.08和2.60±0.56。患者的平均舒张末期速度(EDV)明显高于对照组(P<0.0001),患者和对照组的平均峰值收缩速度(PSV)没有显著差异(P=0.97)。与绝经后患者相比,绝经前患者和对照者的RI和PI显著较低,PSV和EDV显著较高。结论:子宫颈癌症患者的子宫动脉多普勒血流参数与健康对照组相比存在显著差异,且这些参数受女性更年期状况和宫颈肿块大小的影响,以及癌症患者的治疗后评价。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Doppler ultrasound evaluation of blood flow patterns of the uterine arteries in pre- and postmenopausal women with cervical cancer and controls in Zaria
Background: Cervical cancer remains an important health issue, especially in the developing countries that account for about 85% of the world burden of cervical cancer. Finding a role for Doppler ultrasound in the evaluation of these patients may reduce the cost and improve access to management. Aim: The study aimed at evaluating the Doppler flow parameters in pre- and postmenopausal patients with cervical cancer when compared to normal controls in a teaching hospital in Nigeria. Methodology: This is a prospective case–control observational study conducted over a period of 7 months (August 2016–February 2017) in Ahmadu Bello University Teaching Hospital, Zaria, Nigeria. Eighty-one patients with cervical cancer and 81 age-matched controls had a transabdominal Doppler ultrasound examination of the main uterine arteries. The data were analyzed using SPSS version 20.0, Chicago, Illinois, USA. Statistical differences in the uterine artery indices between two groups were tested, andP < 0.05 was considered as statistically significant. Results: The mean resistive index (RI) and pulsatility index (PI) of the patients were 0.64 ± 0.12 and 1.26 ± 0.31, respectively, and of controls were 0.88 ± 0.08 and 2.60 ± 0.56, respectively. These showed significantly lower values in patients than the controls (P < 0.0001). The mean end-diastolic velocity (EDV) was significantly higher in patients than the controls (P < 0.0001). There was, however, no significant difference in the mean peak systolic velocity (PSV) in patients and controls (P = 0.97). Both premenopausal patients and controls had significantly lower RI and PI and significantly higher PSV and EDV compared to their postmenopausal counterpart. Conclusion: The findings showed that significant differences exist in the uterine artery Doppler flow parameters in patients with cervical cancer compared to the healthy controls and that these parameters are influenced by menopausal status of the women and the size of the cervical mass. Hence, Doppler helps in staging, prognosticating, and posttreatment evaluation of patients with cervical cancer.
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来源期刊
West African Journal of Radiology
West African Journal of Radiology RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING-
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