A Rare Case of Acquired Hemophilia, Presenting with Postpartum Hemorrhage

Acquired Hemophilia A (AHA) is a rare but serious bleeding disorder caused by autoantibody (inhibitory) against factor 8 (FVIII). The incidence of the disease is increasing with age, and is seen between 9-15/1,000,000 over 65 years of the age, while it is about 0.3/1,000,000 per year under 65 years of the age. The patient and his family usually do not have any known bleeding diathesis [1,2]. The disease is idiopathic in 40-50% of the cases, while many etiological factors play a role in the remainder. The main etiological factors according to frequency can be listed as; autoimmune diseases, malignancies (solid tumors, hematological neoplasm’s), pregnancy, especially in the postpartum period, drugs, vaccination and respiratory system diseases [1,2]. AHA presenting with postpartum hemorrhage constitutes 6-21% of the all cases [3].