Study on the pharmacodynamics of wound repair ointment in promoting wound healing in rats

Objective： To study pharmacodynamics of the wound repair ointment in promoting wound healing in rats.Methods： Healthy SD rats were selected to establish general wound model and burn and scald wound model.After cleaning，drugs were administrated，wound surfaces were covered with sterile gauze，fixed with medical tape，and dressing changed daily until all wounds healed.Then，healing time and healing rate were investigated.Evaluations on the wound surface healing of the affected sites were made in accordance with the inflammatory exudate，granulation tissue regeneration and epithelial regeneration.Histopathological changes of the wound surfaces were observed by hematoxylin-eosin（HE） staining.Results： The wound repair ointment could shorten the time required for wound healing and wound scabbing，reduce wound size，and alleviate skin scar hyperplasia.Conclusion： The wound repair ointment has obvious effect on the promotion of wound healing.