一名年轻患者的无症状慢性A型大型上行胸主动脉瘤夹层

R. T. Tung, J. Heyns, Lynne A. Dryer, Barbara Eitutis
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引用次数: 1

摘要

引言胸主动脉夹层(TAD)在普通人群中的发病率非常低,每年每100000人中有2.6-3.5例,但它与高死亡率和发病率有关。1-3根据其发病性质和解剖位置,TAD分为急性或慢性斯坦福A型夹层,涉及升主动脉和左锁骨下动脉远端的B型。4,5急性A型夹层具有高度致死性,30天死亡率为50%,而B.2型的死亡率为10%。大多数急性TAD患者突然出现严重的胸部、腹部或背部疼痛,但6.4%的患者可能患有无痛性夹层。6大多数TAD患者年龄较大,平均年龄为63岁,而只有7%的患者年龄小于40岁。7 TAD的常见易感因素是高血压、动脉粥样硬化和心脏手术史2,而在年轻患者中,他们更可能患上马凡氏综合征、,和既往主动脉手术。7我们报告了一例健康的年轻男性退伍军人,他表现为无症状的慢性a型大主动脉瘤夹层,并伴有严重主动脉反流(AR)。在这名患者身上发现了一些以慢性、严重AR为特征的体征。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Asymptomatic, Chronic Type-A Dissection of a Large Ascending Thoracic Aortic Aneurysm in a Young Patient
INTRODUCTION Incidence of thoracic aortic dissection (TAD) in the general population is very low, ranging from 2.6 3.5 cases per 100,000 persons per year, but it is associated with a high rate of mortality and morbidity.1-3 Based on the nature of its onset and anatomical location, TAD is classified as either acute or chronic Stanford type-A dissection involving the ascending aorta and type-B distal to the left subclavian artery.4,5 Acute type-A dissection is highly lethal with a 30-day mortality of 50% compared to 10% of type B.2 Most acute TAD patients presented with a sudden onset of severe chest, abdominal, or back pain, but 6.4% of them may have painless dissection.6 The majority of patients with TAD were older with a mean age of 63 years while only 7% of them were less than 40 years of age.7 Common predisposing factors for TAD are hypertension, atherosclerosis, and a history of cardiac surgery2, while in young patients they are more likely Marfan’s syndrome, bicuspid aortic valve, and prior aortic surgery.7 We report a case of a healthy, young male veteran who presented with asymptomatic, chronic type-A dissection of a large aortic aneurysm, complicated by severe aortic regurgitation (AR). Several physical signs characteristic of chronic, severe AR were found in this patient.
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