黄曲霉绿色合成纳米银及其抗菌性能研究

IF 1 Q4 ENGINEERING, CHEMICAL

Chemical Product and Process Modeling Pub Date : 2023-01-02 DOI:10.1515/cppm-2022-0054

Dinesh Reddy Gopa, Kalyani Pullapukuri

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引用次数: 2

摘要

摘要银纳米颗粒(Ag-NPs)的合成方法有很多，但由于其体积大、表面积小，导致其催化活性下降。因此，本文报道了真菌介导的Ag-NPs合成。通过XRD、SEM、EDS、UV-Vis等对合成的Ag-NPs进行了表征，研究了Ag-NPs的粒径、表面形貌、结晶性质、相形成等，得到的Ag-NPs粒径为41.9 nm。研究了合成的Ag-NPs对热原链球菌、金黄色葡萄球菌、凝固芽孢杆菌、肺炎克雷伯菌、谷氨酸冠状杆菌等多种细菌的抑菌效果。Ag-NPs是一种优良的广谱抗菌剂。更突出的是，由黄曲霉产生的Ag-NPs对某些病原体表现出强大的抗菌活性。凝结芽孢杆菌在80 μg/mL浓度下的最大抑菌带为25.16±0.80，标准抗生素在30 μg/mL浓度下的最大抑菌带为26.66±1.22。

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Green synthesis of silver nanoparticles from Aspergillus flavus and their antibacterial performance

Abstract Many methods have been developed for the synthesis of silver nanoparticles (Ag-NPs), yet disadvantages are there to declined their catalytic activity due to the large size with small surface area. Hence, herein, the fungus mediated synthesis of Ag-NPs has been reported. The synthesized Ag-NPs were further characterized by XRD, SEM, EDS, and UV–Vis spectroscopy to study the particle size, surface, crystalline nature, phase formation of Ag-NPs and the produced particles were found to be 41.9 nm. The antibacterial efficiency of synthesized Ag-NPs was examined on various bacteria including Streptococcus pyrogenes, Staphylococcus aureus, Bacillus coagulans, Klebsiella pneumoniae and Corynibacterium glutamicum. The Ag-NPs could be considered as excellent broad-spectrum antibacterial agent. More prominently, the Ag-NPs produced by Aspergillus flavus exhibited potent antibacterial activity against certain pathogens. Bacillus coagulans exhibited maximum zone of inhibition 25.16 ± 0.80 at 80 μg/mL with respective to the standard antibiotic 26.66 ± 1.22 at 30 μg/mL concentration.

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来源期刊

Chemical Product and Process Modeling ENGINEERING, CHEMICAL-

CiteScore

2.10

自引率

11.10%

发文量

期刊介绍： Chemical Product and Process Modeling (CPPM) is a quarterly journal that publishes theoretical and applied research on product and process design modeling, simulation and optimization. Thanks to its international editorial board, the journal assembles the best papers from around the world on to cover the gap between product and process. The journal brings together chemical and process engineering researchers, practitioners, and software developers in a new forum for the international modeling and simulation community. Topics: equation oriented and modular simulation optimization technology for process and materials design, new modeling techniques shortcut modeling and design approaches performance of commercial and in-house simulation and optimization tools challenges faced in industrial product and process simulation and optimization computational fluid dynamics environmental process, food and pharmaceutical modeling topics drawn from the substantial areas of overlap between modeling and mathematics applied to chemical products and processes.