脑血流动力学对肝性脑病现状及预测的影响

B. Fishman, V. Veber, V. Kulikov, M. Hapman, О. Denisova, K. Nikolaeva, V. Zurabov, M. Yukhno, O. Lole, P. Starikov
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引用次数: 0

摘要

在不同年龄的Child-Pugh型A、B、C型病毒性肝硬化患者中,随着慢性脑血管功能不全的发展,慢性肝性脑病可伴发各阶段的循环系统疾病。热坦试验持续时间大于200秒,血流半球不对称大于40%,大脑中动脉盆区血流速度参数下降及血管阻力指标低于参考值与肝性脑病预后不良有关。认知和循环功能障碍的程度与肝硬化代偿期有关。随着循环障碍和肝硬化代偿期的缩短,从逻辑思维能力和注意时间和空间定向障碍的认知障碍程度增加。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cerebral Hemodynamics Influence on the Current and Prediction of Hepatic Encephalopathy
Among patients of different ages with hepatocirrhosis of A, B, C virus viral etiology in Child-Pugh, chronic hepatic encephalopathy of all stages may occur along with discirculatory disorders with the development of chronic cerebrovascular insufficiency. The Reitan test duration is more than 200 seconds, blood flow hemispheric asymmetry is more than 40%, the decrease in the velocity parameters of the blood flow and the indices of vascular resistance in the basins of the middle cerebral arteries decrease below the reference values are associated with the adverse hepatic encephalopathy prognosis. The degrees of cognitive and discirculatory disorders are interrelated with the compensation stages for hepatocirrhosis. An increase of cognitive impairment degree from the logical thinking ability and attention to time and space disorientation is registered along with discirculatory disorders and cirrhosis compensation stage decrease.
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