漫长而曲折的道路:我个人通往催产素的旅程,一去不复返

IF 2.1 Q3 ENDOCRINOLOGY & METABOLISM
Donatella Marazziti
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引用次数: 0

摘要

本论文是作者回顾她的科学途径,导致她走向催产素研究的个人叙述。我的工作开始于一项开创性的研究,该研究表明浪漫的恋人体内血清素转运蛋白的数量减少。这个意想不到的发现激发了我对人类情感和感觉的神经生物学的兴趣,并显著地将我的研究重点从疾病转移到“爱”背后的生理状态。在此期间,越来越多的实验数据拓宽了催产素的活动范围,从女性功能,如分娩和哺乳,到调节压力和免疫系统。文献也开始揭示催产素在安全感和幸福感方面的重要作用,这些过程对爱情和生存都至关重要。在此,我建议未来的研究应该解开关于催产素在人性中的确切作用的不同新出现的问题,以及它在不同生理条件和病理状态下可能的治疗应用。了解这些,反过来,有可能改善个人和社会的生活。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A long and winding road: My personal journey to oxytocin with no return

The present paper is the personal narration of the author reviewing her scientific pathways that led her toward the study of oxytocin. My work began with a pioneering study showing a decreased number of the serotonin transporter proteins in romantic lovers. This unexpected finding promoted my interest in the neurobiology of human emotions and feelings, and significantly shifted my research focus from diseases to physiological states that underlie “love.” During this time increasing experimental data broadened the spectrum of activities of oxytocin from female functions, such as parturition and lactation, to modulation of the stress and immune system. The literature also began to reveal an important role for oxytocin in a sense of safety and wellbeing, processes that are critical to both love and survival. I suggest here that future studies should disentangle different emerging questions regarding the exact role of oxytocin within human nature, as well as its possible therapeutic applications in different physiological conditions and pathological states. Understanding these, in turn, holds the potential to improve the lives of both individuals and societies.

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来源期刊
Comprehensive psychoneuroendocrinology
Comprehensive psychoneuroendocrinology Psychiatry and Mental Health
CiteScore
3.10
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审稿时长
62 days
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