糖尿病的神经超声表现取决于解剖位置和糖尿病的类型

IF 2 Q3 NEUROSCIENCES
Marianna Tóth , Annamária Szőke , Zsuzsanna Arányi
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引用次数: 1

摘要

目的对1型和2型糖尿病患者的神经大小及其影响因素进行前瞻性超声研究。方法采用高分辨率超声对26例1型糖尿病患者和76例2型糖尿病患者及50例对照者的上肢和下肢运动神经和感觉神经的14个测点进行测量。所有糖尿病患者均接受电生理检查,以检查是否存在多发性神经病变。结果2型糖尿病患者表现出明显的轻度/中度弥漫性神经扩张,压迫部位比非压迫部位、上肢比下肢更明显(DM2与对照组的p值:<0.001)。1型糖尿病患者仅在一个压迫部位(腕正中神经; = 0.002页)。有无多发神经病变患者间无明显差异。结论糖尿病患者神经大小的主要预测因素是解剖位置(即压迫部位与非压迫部位、上肢与下肢)和糖尿病类型。变化发生在多神经病变的电生理体征被检测到之前。意义神经超声可能有助于早期识别糖尿病的神经性并发症。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Nerve ultrasonographic findings in diabetes mellitus are determined by anatomical location and type of diabetes

Objective

A prospective ultrasound study to analyze nerve size and its modifying factors in type 1 and type 2 diabetes mellitus.

Methods

The cross-sectional areas (CSAs) of motor and sensory nerves in both upper and lower limbs were measured at 14 measurement points, using high resolution ultrasound in 26 patients with type 1 and 76 patients with type 2 diabetes, and in 50 control subjects. All diabetic patients underwent electrophysiological assessment to check for the presence of polyneuropathy.

Results

Significant mild/moderate diffuse nerve enlargement was demonstrated in type 2 diabetes, more pronounced at compression sites versus non-compression sites, and on the upper limbs versus lower limbs (p value for pooled DM2 v. control group: <0.001). In type 1 diabetes, nerve enlargement was found only at one compression site (median nerve wrist; p = 0.002). No significant difference was found between patients with or without polyneuropathy.

Conclusions

The primary predictors of nerve size in diabetes are anatomical location (i.e. compression sites versus non-compression sites, upper versus lower limbs) and type of diabetes. Changes occur before the electrophysiological signs of polyneuropathy are detected.

Significance

Nerve ultrasound may contribute to early recognition of the neuropathic complications of diabetes.

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来源期刊
CiteScore
3.90
自引率
0.00%
发文量
47
审稿时长
71 days
期刊介绍: Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.
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