J. Hao, Bin xu, Yonggang Wang, Yanping Li, J. Zhao
{"title":"黄体期支持期间补充雌二醇对体外受精临床结果的影响：系统评价和荟萃分析","authors":"J. Hao, Bin xu, Yonggang Wang, Yanping Li, J. Zhao","doi":"10.33696/gynaecology.1.005","DOIUrl":null,"url":null,"abstract":"This study aimed to clarify whether estradiol (E2) supplementation as luteal phase support (LPS) has benefit effect on the clinical outcomes after IVF/ICSI. A meta-analysis was conducted. E2+P group had significant higher CPR and ongoing PR than that of P-only group. GnRH-a protocol group had a significant higher CPR and ongoing PR with E2+P, whereas GnRH-ant protocol group had no difference in CPR, ongoing PR, IR, and AR among E2+P and Ponly groups. So, E2 supplementation as LPS has beneficial effect on the clinical outcomes only during cycles with GnRH-a protocol. Background","PeriodicalId":93076,"journal":{"name":"Archives of obstetrics and gynaecology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2020-06-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Impact of Estradiol Supplementation during Luteal Phase Support on the In vitro Fertilization Clinical Outcome: Systematic Review and Meta-Analysis\",\"authors\":\"J. Hao, Bin xu, Yonggang Wang, Yanping Li, J. Zhao\",\"doi\":\"10.33696/gynaecology.1.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"This study aimed to clarify whether estradiol (E2) supplementation as luteal phase support (LPS) has benefit effect on the clinical outcomes after IVF/ICSI. A meta-analysis was conducted. E2+P group had significant higher CPR and ongoing PR than that of P-only group. GnRH-a protocol group had a significant higher CPR and ongoing PR with E2+P, whereas GnRH-ant protocol group had no difference in CPR, ongoing PR, IR, and AR among E2+P and Ponly groups. So, E2 supplementation as LPS has beneficial effect on the clinical outcomes only during cycles with GnRH-a protocol. Background\",\"PeriodicalId\":93076,\"journal\":{\"name\":\"Archives of obstetrics and gynaecology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-06-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of obstetrics and gynaecology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.33696/gynaecology.1.005\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of obstetrics and gynaecology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33696/gynaecology.1.005","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Impact of Estradiol Supplementation during Luteal Phase Support on the In vitro Fertilization Clinical Outcome: Systematic Review and Meta-Analysis
This study aimed to clarify whether estradiol (E2) supplementation as luteal phase support (LPS) has benefit effect on the clinical outcomes after IVF/ICSI. A meta-analysis was conducted. E2+P group had significant higher CPR and ongoing PR than that of P-only group. GnRH-a protocol group had a significant higher CPR and ongoing PR with E2+P, whereas GnRH-ant protocol group had no difference in CPR, ongoing PR, IR, and AR among E2+P and Ponly groups. So, E2 supplementation as LPS has beneficial effect on the clinical outcomes only during cycles with GnRH-a protocol. Background
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