儿童严重急性呼吸系统综合征冠状病毒2型相关多系统炎症综合征的治疗指南:文献综述和专家意见

IF 0.3 Q4 PEDIATRICS
A. Ghodsi, Mehrdad Sarabi, A. Malek, A. Khakshour
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引用次数: 3

摘要

摘要儿童多系统炎症综合征(MIS-C)是一种系统性疾病,似乎与严重急性呼吸综合征冠状病毒2型(严重急性呼吸系统综合征冠状病毒冠状病毒2型)有关。自2020年4月以来,包括欧洲、亚洲、拉丁美洲和北美在内的世界各地都有多份关于患有这种新疾病的儿童的报告。该综合征的症状与川崎病的临床表现相似;因此,川崎病的治疗以及支持性护理是MIS-C儿童早期认识的选择。重要的是,根据来自队列、试验和专家意见的可靠数据,准确确定儿童感染新冠肺炎的风险及其严重程度,并确认该综合征的管理。在当前的综述中,我们总结了MIS-C的当前管理指南,并提出了我们自己的方案,以回答新冠肺炎大流行期间有关MIS-C管理的一些临床问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current Treatment Guidelines of SARS-CoV-2 Related Multisystem Inflammatory Syndrome in Children: A Literature Review and Expert Opinion
Abstract Multisystem inflammatory syndrome in children (MIS-C) is a systemic disorder that seems to be associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Since April 2020, there have been multiple reports about children with this new condition worldwide, including Europe, Asia, Latin America, and North America. The symptoms of this syndrome mimic the clinical manifestations of Kawasaki disease; therefore, the treatment of Kawasaki disease, as well as supportive care, was the management of choice in children with MIS-C in the early days of recognizing it. It is important to precisely ascertain the risk of COVID-19 infection and its severity in children and to acknowledge the management of this syndrome, with reliable data from cohorts, trials, and experts' opinions. In the current review, we summarize the current management guidelines for MIS-C and present our own protocol to answer some clinical questions regarding MIS-C management during the COVID-19 pandemic.
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