维生素D对新冠肺炎疾病有预防或治疗潜力吗?:简评

A. Mishra, E. Tuladhar, V. Sharma, M. Raut, A. Bhattarai, M. Tamang, B. Yadav
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引用次数: 0

摘要

2020年,世界卫生处于COVID-19大流行及其不利后果的控制之下,2021年仍将继续。大多数国家已经被封锁或正在经历不同形式的封锁,以防止传染性病毒SARS-CoV-2的传播。迄今为止,没有具体的治疗或疫苗接种预防措施。世界卫生组织已经批准了一些紧急使用的疫苗。尽管如此,sars冠状病毒内部突变的出现给疫苗开发商带来了挑战。无论是传染性疾病还是非传染性疾病,所有疾病都有一个炎症方面来警告身体系统,同时还有一个抗炎平衡机制,通过免疫调节或抗氧化储备来减少有害影响。还寻求在预防和治疗层面加强抗炎方面对抗新型疾病covid - 19的方法。其中一种方法是推荐微量营养素维生素D,其免疫调节作用已在许多疾病条件下得到很好的认识。本文旨在探讨维生素D易感性与COVID-19临床结局之间的关系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Does Vitamin D has Preventive or Treatment Potential to Covid-19 Illness?: A Brief Review
The world’s health in 2020 was in the grip of the COVID-19 pandemic and its adverse consequences and is still continuing in 2021. Most countries have been locked down or going through different forms of lockdown to prevent the transmission of the infectious virus SARS-CoV-2. To date, there is no specific treatment or vaccination preventive measures. World Health Organization has approved few vaccines for emergency use. Still, the emergence of mutations within SARS-CoV has put forward challenges for vaccine developers. Whether infectious or non-infectious, all diseases have an inflammatory aspect to alarm the body system along with an anti-inflammatory counterbalance mechanism to minimize harmful effects whether through immune modulation or antioxidant reserves. An approach to counteract the novel disease, COVID19, was also sought in enhancing the anti-inflammatory aspect, at the level of prevention and at the level of treatment. One of the methodologies was the recommendation of micronutrient Vitamin D whose immune-modulatory role has been well appreciated in many disease conditions. This short review aims to explore the relationship between vitamin D status through susceptibility and clinical outcomes of COVID-19.
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