双歧杆菌三联活颗粒联合蒙脱石散治疗小儿腹泻

IF 0.4 4区医学 Q4 NUTRITION & DIETETICS

Current Topics in Nutraceutical Research Pub Date : 2023-07-07 DOI:10.37290/ctnr2641-452x.21:272-276

Wendi Jin, Er-te Yu, Yunbing Lu, Zhaolin Wang, Li Huang, X. Qiao

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引用次数: 0

摘要

本研究旨在评价双歧杆菌三联活菌颗粒剂联合蒙脱石粉治疗儿童腹泻的效果。为此，将60名腹泻患儿分为两组，大小相同，一组单独服用蒙脱土粉(对照组)，另一组服用蒙脱土粉加双歧杆菌三联活菌颗粒(治疗组)。治疗组儿童的腹泻总体缓解程度显著提高，发热、腹泻、腹痛和呕吐的持续时间较短，大便特征和大便频率的恢复时间也较短。治疗组血清c反应蛋白、白细胞介素-4、白细胞介素-6水平低于对照组，免疫球蛋白A、免疫球蛋白G、免疫球蛋白M水平高于对照组(P < 0.05)。治疗组的不良反应明显少于对照组。综上所述，双歧杆菌三联活菌颗粒剂联合蒙脱石散治疗小儿腹泻在临床上具有优势。

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Bifidobacterium Triple Viable Granules Combined with Montmorillonite Powder in the Therapy of Children with Diarrhea

This study was designed to evaluate the effect of Bifidobacterium triple viable granules combined with montmorillonite powder in children with diarrhea. To this end, 60 children with diarrhea were divided into two groups of equal size, with one receiving montmorillonite powder alone (control) and the other receiving montmorillonite powder plus Bifidobacterium triple viable granules (treatment). The children in the treatment group experienced significantly higher overall relief from diarrhea that was associated with shorter durations of fever, diarrhea, abdominal pain, and vomiting, as well as shorter recovery times for stool characters and stool frequency. Also, the serum levels of C-reactive protein, Interleukin-4, and Interleukin-6 were lower, while Immunoglobulin A, Immunoglobulin G, and Immunoglobulin M levels were higher in the treatment group than the control group (P < 0.05). There were far fewer adverse reactions in the treatment group than in the control group. In summary, Bifidobacterium triple viable granules combined with montmorillonite powder are clinically superior in treating children with diarrhea.

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来源期刊

Current Topics in Nutraceutical Research 医学-药学

CiteScore

1.10

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Current Topics in Nutraceutical Research is an international, interdisciplinary broad-based peer reviewed scientific journal for critical evaluation of research on chemistry, biology and therapeutic applications of nutraceuticals and functional foods. The major goal of this journal is to provide peer reviewed unbiased scientific data to the decision makers in the nutraceutical and food industry to help make informed choices about development of new products. To this end, the journal will publish two types of review articles. First, a review of preclinical research data coming largely from animal, cell culture and other experimental models. Such data will provide basis for future product development and/or human research initiatives. Second, a critical evaluation of current human experimental data to help market and deliver the product for medically proven use. This journal will also serve as a forum for nutritionists, internists, neurologists, psychiatrists, and all those interested in preventive medicine. The common denominator of all of the topic to be covered by the journal must include nutraceuticals and/functional food. The following is an example of some specific areas that may be of interest to the journal. i) Role of vitamins, minerals, antioxidants and phytonutrients on cardiovascular health, cancer, diabetes, ocular health, mental health, men’s health, women’s health, infant nutrition, ii) Role of herbals on human health, iii) Dietary supplements and sleep, iv) Components of diet that may have beneficial effect on human health, v) regulation of apoptosis and cell viability, vi) Isolation and characterization of bioactive components from functional foods, vii) Nutritional genomics, and viii) Nutritional proteomics.