上海市92932例人乳头瘤病毒的流行及基因型分布

IF 2.1 4区医学 Q3 VIROLOGY

Future Virology Pub Date : 2023-06-16 DOI:10.2217/fvl-2022-0180

Ya-Ping Hou, Cheng Fan, Qing-Qing Jiang, Lei Wu, Ying Luo

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引用次数: 0

摘要

目的：人乳头瘤病毒（HPV）是宫颈上皮内瘤样病变（CIN）和癌症（CC）等高级别病变和致癌的最常见原因。不同地理区域HPV感染的患病率和基因型分布差异很大。患者与方法：本研究从2017年1月至2021年12月招募了92932名患者，并分析了HPV基因型的患病率和分布。结果：18038例（19.41%）HPV阳性。男性和女性之间的感染率没有显著差异（19.05比19.41%）。最常见的HPV亚型是HPV52、HPV58、HPV16、HPV53、HPV51和HPV81。在HPV阳性患者中，HPV的单一感染占主导地位。结论：我们的研究结果表明，HPV亚型的患病率和分布具有明显的区域特异性和年龄特异性特征。

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Prevalence and genotype distribution of human papillomavirus in 92,932 cases in Shanghai, China

Aim: Human papillomavirus (HPV) is the most common cause of high-grade lesions and carcinogenesis such as cervical intraepithelial neoplasia (CIN) and cervical cancer (CC). The prevalence and genotype distribution of HPV infection varies greatly in different geographical areas. Patients & methods: This study enrolled 92,932 patients from January 2017 to December 2021 and analyzed the prevalence and distribution of HPV genotypes. Results: 18038 (19.41%) specimens were HPV-positive. No significant difference in infection rates between men and women (19.05 vs 19.41%). The most prevalent HPV subtypes are HPV52, HPV58, HPV16, HPV53, HPV51 and HPV81. Single infection of HPV has dominated in HPV-positive patients. Conclusion: Our results show that the prevalence and distribution of HPV subtypes have obvious region-specific and age-specific characteristics.

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来源期刊

Future Virology 医学-病毒学

CiteScore

4.00

自引率

3.20%

发文量

审稿时长

6-12 weeks

期刊介绍： Future Virology is a peer-reviewed journal that delivers essential information in concise, at-a-glance article formats. Key advances in the field are reported and analyzed by international experts, providing an authoritative but accessible forum for this ever-expanding area of research. It is an interdisciplinary forum for all scientists working in the field today.