会见我们的编辑委员会成员

IF 1.5 Q3 PERIPHERAL VASCULAR DISEASE
G. Tse
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引用次数: 0

摘要

Gary于1982年在John E.Bartmess博士的指导下获得印第安纳大学物理/有机化学博士学位,使用离子回旋共振光谱法研究气相离子化学。在获得博士学位后,他与加拿大阿尔伯塔大学的Paul Kebarle博士一起进行了博士后研究,使用高压质谱法研究气相离子化学。Gary于1985年加入强生子公司杨森制药研发公司。在杨森制药32年的研发生涯中,Gary管理着药物研发部门的各种职能。这些功能包括NMR、GC/MS和LC/MS/MS光谱组、药物化学中间体组、大规模分离组、药物发现体内/体外PK/ADME组和化合物管理组。他的研究兴趣主要涉及使用先进的光谱和色谱技术对新药靶点和药物实体进行化学和生物学表征。目前,他正在致力于建立靶向和非靶向代谢组学方法,以了解“开”和“关”靶效应,从而提高药物疗效并降低药物毒性。他著有150多份出版物、两项专利、50多份海报演示,并在大学、公司和会议上发表了40多场受邀演讲。他是《药物设计与发现前沿》(第1-4卷)的联合编辑,《药物发现优化:体外方法》(第1-2卷)的编辑。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Meet Our Editorial Board Member
Gary received his Ph.D. in physical/organic chemistry from Indiana University in 1982 under the direction of Dr. John E. Bartmess using Ion Cyclotron Resonance Spectrometry to study gas-phase ion chemistry. Following his Ph.D., he performed postdoctoral research with Dr. Paul Kebarle at the University of Alberta in Canada using High-Pressure Mass Spectrometry to study gas-phase ion chemistry. Gary joined Janssen Pharmaceutical Research and Development a subsidiary of Johnson & Johnson in 1985. During his 32-year career with Janssen Pharmaceutical R & D, Gary has managed a variety of functions within the drug discovery units. These functions include the NMR, GC/MS & LC/MS/MS spectroscopy group, the medicinal chemistry intermediates group, the large-scale separation group, the drug discovery in-vivo/in-vitro PK/ADME groups and the compound management group. His research interests primarily involve the use of advanced spectrometric and chromatographic techniques to chemically and biologically characterize new drug targets and drug entities. Presently, he is working on establishing targeted and untargeted metabolomic methods to understand “on” and “off” target effects to improve drug efficacy and reduce drug toxicity. He is the author of over 150 publications, two patents, over 50 poster presentations, and has given over 40 invited talks at universities, companies, and conferences. He is the co-editor of Frontier in Drug Design & Discovery (volumes 1-4), editor of Optimization in Drug Discovery: In-Vitro Methods (volumes 1-2).
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来源期刊
Current Hypertension Reviews
Current Hypertension Reviews PERIPHERAL VASCULAR DISEASE-
CiteScore
4.80
自引率
0.00%
发文量
26
期刊介绍: Current Hypertension Reviews publishes frontier reviews/ mini-reviews, original research articles and guest edited thematic issues on all the latest advances on hypertension and its related areas e.g. nephrology, clinical care, and therapy. The journal’s aim is to publish the highest quality review articles dedicated to clinical research in the field. The journal is essential reading for all clinicians and researchers in the field of hypertension.
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