点评:Huang S.等。“阿尔茨海默病的生物流体生物标志物:进展、问题和观点。”神经科学通报(2022)

Urine (Amsterdam, Netherlands) Pub Date : 2022-01-01 DOI:10.1016/j.urine.2022.07.001

He Jin , Rong Wang

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引用次数: 0

摘要

Huang S.等人基于A-T-N-X框架回顾性描述了生物标志物的最新进展，A-T-N分别代表淀粉样蛋白- tau -神经变性，X代表与阿尔茨海默病(AD)整个病理过程相关的中枢或外周生物标志物。A-T-N-X的框架对于了解AD的全谱具有重要意义，但我们仍然要强调尿液生物标志物对于AD的早期识别和有效管理的重要性。

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Comments on: Huang S. et al. “Biofluid Biomarkers of Alzheimer's disease: Progress, problems, and perspectives.” Neuroscience Bulletin (2022)

This paper by Huang S., et al. has retrospectively described the recent progress in biomarkers based on the A-T-N-X framework, A-T-N respectively represents Amyloid-Tau-Neurodegeneration, X represents biomarkers from central or peripheral related to the whole pathological course of Alzheimer's disease (AD). The framework of A-T-N-X is of great significance for understanding the whole spectrum of AD, but we still want to stress the importance of urine biomarkers for the early identification and effective management of AD.

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来源期刊

Urine (Amsterdam, Netherlands) Health Informatics, Pathology and Medical Technology, Urology

自引率

0.00%

发文量

审稿时长

99 days