性别差异对2型糖尿病患者认知功能的影响

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2022-12-31 DOI:10.37897/rjn.2022.4.14

Anak Agung Ayu Putri Laksmidewi, Valentina Tjandra Dewi

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引用次数: 0

摘要

介绍。女性被认为是痴呆症的一个风险因素。研究性别差异对2型糖尿病(type 2 DM)患者认知功能的影响的研究数量有限，结果不一。本研究旨在确定性别差异对2型糖尿病患者认知障碍(CI)风险的影响。材料和方法。本研究采用病例对照研究设计。连续招募样本。资料分析采用卡方检验和logistic回归，以比值比(OR) (95% CI)表示，显著性水平P <0.05。60例糖尿病患者符合入选标准。双因素分析发现，女性[OR=3.75 (95% CI 1.23-11.38)， P=0.017]、低教育水平和高血压与2型DM CI相关。多因素分析显示，低教育水平和高血压是2型DM CI的独立危险因素。结论。基于本研究，女性性别并不是2型糖尿病患者认知功能障碍的独立危险因素。

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The impact of gender differences on the cognitive function of type 2 Diabetes Mellitus patients

Introduction. Female sex is considered a risk factor for dementia. A limited number of studies have studied the role of gender differences on the cognitive function of type 2 diabetes mellitus (type 2 DM) patients with varying results. This study aims to determine the impact of gender differences on the cognitive impairment (CI) risk in type 2 DM patients. Material and methods. This study used a case-control research design. Samples were recruited consecutively. Data were analyzed by Chi-square test and logistic regression, expressed in odds ratio (OR) (95% CI) with a significance level of P <0.05 Outcomes. Sixty patients with diabetes met the eligibility criteria. The bivariate analysis found that female gender [OR=3.75 (95% CI 1.23-11.38), P=0.017], low education level, and hypertension were associated with CI in type 2 DM. Independent risk factors for CI in type 2 DM from the multivariate analysis were low education level and hypertension. Conclusions. Based on this study, female gender is not an independent risk factor for cognitive dysfunction in patients with type 2 DM.

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来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.